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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nodgo</journal-id><journal-title-group><journal-title xml:lang="ru">Российский журнал детской гематологии и онкологии (РЖДГиО)</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Pediatric Hematology and Oncology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2311-1267</issn><issn pub-type="epub">2413-5496</issn><publisher><publisher-name>LTD “Graphica”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21682/2311-1267-2024-11-3-60-65</article-id><article-id custom-type="elpub" pub-id-type="custom">nodgo-1072</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LITERATURE REVIEWS</subject></subj-group></article-categories><title-group><article-title>Этические и юридические вопросы сохранения детской онкофертильности</article-title><trans-title-group xml:lang="en"><trans-title>Ethical and legal issues of preserving childhood oncofertility</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1886-3993</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лавринович</surname><given-names>О. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Lavrinovich</surname><given-names>O. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ольга Евгеньевна Лавринович - к.м.н., научный сотрудник отделения онкогинекологии, заведующая лабораторией онкофертильности и отделением малой хирургии НМИЦ онкологии им. Н.Н. Петрова.</p><p>197758, Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68</p></bio><bio xml:lang="en"><p>Cand. of Sci. (Med.), Research Associate of the Department of Oncogynecology, Head of the Laboratory of Oncofertility, Head of the Department of Minor Surgery at N.N. Petrov NMRCO.</p><p>68 Leningradskaya St., Pesochny, Saint Petersburg, 197758</p></bio><email xlink:type="simple">olgalav1973@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-0216-2727</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Карицкий</surname><given-names>А. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Karitsky</surname><given-names>A. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., заместитель директора по лечебной работе НМИЦ онкологии им. Н.Н. Петрова, ResearcherID: 338551.</p><p>197758, Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68</p></bio><bio xml:lang="en"><p>Cand. of Sci. (Med.), Deputy Director for Medical Work, ResearcherID: 338551.</p><p>68 Leningradskaya St., Pesochny, Saint Petersburg, 197758</p></bio><email xlink:type="simple">9515321@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0000-9472-5704</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Татищева</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Tatishcheva</surname><given-names>Yu. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.б.н., врач-эмбриолог НМИЦ онкологии им. Н.Н. Петрова, ResearcherID: 120594.</p><p>197758, Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68</p></bio><bio xml:lang="en"><p>Cand. of Sci. (Biol.), Embryologis, ResearcherID: 120594.</p><p>68 Leningradskaya St., Pesochny, Saint Petersburg, 197758</p></bio><email xlink:type="simple">jul_taty@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0390-8498</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кулева</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kulyova</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, заведующая детским онкологическим отделением, ведущий научный сотрудник научного отдела инновационных методов терапевтической онкологии и реабилитации, профессор учебно-методического отдела НМИЦ онкологии им. Н.Н. Петрова, заведующая кафедрой онкологии, детской онкологии и лучевой терапии СПбГПМУ.</p><p>197758, Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68</p><p>194100, Санкт-Петербург, ул. Литовская, 2</p></bio><bio xml:lang="en"><p>Dr. of Sci. (Med.), Professor, Head of Pediatric Oncology Department, Leading Researcher of the Research Department of Innovative Therapeutic Oncology and Rehabilitation Methods, Professor of the Training and Methodology Department N.N. Petrov NMRCO, Head of the Department of Oncology, Pediatric Oncology and Radiation Therapy at St. Petersburg SPMU.</p><p>68 Leningradskaya St., Pesochny, Saint Petersburg, 197758; 2 Litovskaya St., Saint Petersburg, 194100</p></bio><email xlink:type="simple">kulevadoc@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Национальный медицинский исследовательский центр онкологии имени Н.Н. Петрова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>N.N. Petrov National Medical Research Center of Oncology, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ «Национальный медицинский исследовательский центр онкологии имени Н.Н. Петрова» Минздрава России; ФГБОУ ВО «Санкт-Петербургский государственный педиатрический медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>N.N. Petrov National Medical Research Center of Oncology, Ministry of Health of Russia; Saint Petersburg State Pediatric Medical University, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>30</day><month>10</month><year>2024</year></pub-date><volume>11</volume><issue>3</issue><fpage>60</fpage><lpage>65</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Лавринович О.Е., Карицкий А.П., Татищева Ю.А., Кулева С.А., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Лавринович О.Е., Карицкий А.П., Татищева Ю.А., Кулева С.А.</copyright-holder><copyright-holder xml:lang="en">Lavrinovich O.E., Karitsky A.P., Tatishcheva Y.A., Kulyova S.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nodgo.org/jour/article/view/1072">https://journal.nodgo.org/jour/article/view/1072</self-uri><abstract><p>Обеспечение качества жизни детей после выздоровления является одним из важных аспектов реабилитации. Сохранение фертильности детей, подростков и молодых людей позволит повысить шансы на полноценную жизнь после лечения онкологического заболевания и рождение биологически родного ребенка. Необходимо учитывать, что оценить степень нарушения репродуктивного потенциала и перспективы его восстановления возможно лишь после завершения гонадотоксичного лечения, в то время как применение методов сохранения фертильности имеет большую эффективность до начала онкологической терапии. Сложность обсуждения с маленькими пациентами и их родителями (опекунами) риска снижения или потери репродуктивной функции, методов сохранения фертильности, необходимости принять решение еще об одном, порой инвазивном, вмешательстве, влечет за собой определенные этические и юридические проблемы, которые требуют особого внимания для защиты врачей и пациентов.</p></abstract><trans-abstract xml:lang="en"><p>Providing a better quality of life for the children with cancer after recovery proves to be one and important aspect of rehabilitation. Preserving the fertility of children, adolescents and young adults can improve the chances to lead a full, active life, and have biological children after oncological treatment. It is necessary to consider that the degree of reproductive potential impairment as well as recovery perspectives can be assessed solely after the gonadotoxic therapy completion. Whereas fertility preservation practice proves to be more effective before the oncological treatment. The complexity of discussing with young patients and their parents (custodian parents) the risk of decrease or loss of reproductive function, of fertility preservation methods, of necessity to agree to another possible invasive intervention raises quite a range of ethical and legal problems, which claim special attention on behalf of doctors and patients’ protection.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>дети</kwd><kwd>подростки</kwd><kwd>онкофертильность</kwd><kwd>сохранение фертильности</kwd><kwd>этика</kwd><kwd>юридические аспекты</kwd></kwd-group><kwd-group xml:lang="en"><kwd>children</kwd><kwd>teenagers</kwd><kwd>оncofertility</kwd><kwd>fertility preservation</kwd><kwd>ethics</kwd><kwd>legal aspects</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Исследование проведено без спонсорской поддержки</funding-statement><funding-statement xml:lang="en">The study was performed without external funding</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Мерабишвили В.М., Шахзадова А.О., Кулева С.А., Перелыгин В.В. 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