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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nodgo</journal-id><journal-title-group><journal-title xml:lang="ru">Российский журнал детской гематологии и онкологии (РЖДГиО)</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Pediatric Hematology and Oncology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2311-1267</issn><issn pub-type="epub">2413-5496</issn><publisher><publisher-name>LTD “Graphica”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21682/2311-1267-2026-13-1-91-97</article-id><article-id custom-type="elpub" pub-id-type="custom">nodgo-1267</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ НАБЛЮДЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASES</subject></subj-group></article-categories><title-group><article-title>Юкстагломерулярноклеточная опухоль почки у ребенка 11 лет: описание клинического случая</article-title><trans-title-group xml:lang="en"><trans-title>Juxtaglomerular cell tumor of the kidney in an 11-year-old child: case report</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0006-7276-7675</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кисурина</surname><given-names>Д. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Kisurina</surname><given-names>D. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-детский онколог приемного отделения</p><p>117997, Москва, ул. Саморы Машела, 1</p></bio><bio xml:lang="en"><p>Pediatric Oncologist of Emergency Department </p><p>1 Samory Mashela St., Moscow, 117997</p></bio><email xlink:type="simple">darya.kisurina@dgoi.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9625-8625</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Смирнова</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Smirnova</surname><given-names>L. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-детский онколог отделения клинической онкологии</p><p>117997, Москва, ул. Саморы Машела, 1</p></bio><bio xml:lang="en"><p>Pediatric Oncologist of Department of Clinical Oncology</p><p>1 Samory Mashela St., Moscow, 117997</p></bio><email xlink:type="simple">liliya.smirnova@dgoi.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9788-0504</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Митрофанова</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Mitrofanova</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-патологоанатом патологоанатомического отделения</p><p>117997, Москва, ул. Саморы Машела, 1</p></bio><bio xml:lang="en"><p>Pathologist of Department of Pathology </p><p>1 Samory Mashela St., Moscow, 117997</p></bio><email xlink:type="simple">anna.mitrofanova@dgoi.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0404-6420</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Меркулов</surname><given-names>Н. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Merkulov</surname><given-names>N. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-детский хирург отделения онкологии и детской хирургии</p><p>117997, Москва, ул. Саморы Машела, 1</p></bio><bio xml:lang="en"><p>Pediatric Surgeon of Department of Oncology and Pediatric Surgery </p><p>1 Samory Mashela St., Moscow, 117997</p></bio><email xlink:type="simple">nikolay.merkulov@dgoi.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4042-0125</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Телешова</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Teleshova</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-детский онколог отделения клинической онкологии</p><p>117997, Москва, ул. Саморы Машела, 1</p></bio><bio xml:lang="en"><p>Pediatric Oncologist of Department of Clinical Oncology</p><p>1 Samory Mashela St., Moscow, 117997</p></bio><email xlink:type="simple">margarita.teleshova@dgoi.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8129-0545</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Щербаков</surname><given-names>А. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Shcherbakov</surname><given-names>А. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-рентгенолог рентгенологического отделения</p><p>117997, Москва, ул. Саморы Машела, 1</p></bio><bio xml:lang="en"><p>Physician of Radiology Department </p><p>1 Samory Mashela St., Moscow, 117997</p></bio><email xlink:type="simple">alexey.shcherbakov@dgoi.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4451-3233</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Грачев</surname><given-names>Н. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Grachev</surname><given-names>N. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, генеральный директор</p><p>117997, Москва, ул. Саморы Машела, 1</p></bio><bio xml:lang="en"><p>Dr. of Sci. (Med.), Professor, General Director</p><p>1 Samory Mashela St., Moscow, 117997</p></bio><email xlink:type="simple">nikolay.grachev@dgoi.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3704-8783</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Качанов</surname><given-names>Д. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Kachanov</surname><given-names>D. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., доцент, заведующий отделением клинической онкологии</p><p>117997, Москва, ул. Саморы Машела, 1</p></bio><bio xml:lang="en"><p>Dr. of Sci. (Med.), Associate Professor, Head of the Department of Clinical Oncology</p><p>1 Samory Mashela St., Moscow, 117997</p></bio><email xlink:type="simple">denis.kachanov@dgoi.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Национальный медицинский исследовательский центр детской гематологии, онкологии и иммунологии имени Дмитрия Рогачева» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>03</day><month>04</month><year>2026</year></pub-date><volume>13</volume><issue>1</issue><fpage>91</fpage><lpage>97</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кисурина Д.Д., Смирнова Л.А., Митрофанова А.М., Меркулов Н.Н., Телешова М.В., Щербаков А.П., Грачев Н.С., Качанов Д.Ю., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Кисурина Д.Д., Смирнова Л.А., Митрофанова А.М., Меркулов Н.Н., Телешова М.В., Щербаков А.П., Грачев Н.С., Качанов Д.Ю.</copyright-holder><copyright-holder xml:lang="en">Kisurina D.D., Smirnova L.A., Mitrofanova A.M., Merkulov N.N., Teleshova M.V., Shcherbakov А.P., Grachev N.S., Kachanov D.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nodgo.org/jour/article/view/1267">https://journal.nodgo.org/jour/article/view/1267</self-uri><abstract><sec><title>Актуальность</title><p>Актуальность. Юкстагломерулярноклеточная опухоль (ЮГКО) почки, или ренинома, – доброкачественное новообразование, крайне редко встречающееся у детей. В отличие от других опухолей почек патогенез ЮГКО связан с активацией ренинангиотензиновой системы и клинически проявляется течением стойкой артериальной гипертензии, детерминированной секрецией опухолью ренина. В данной статье представлен клинический случай пациентки 11 лет с ЮГКО почки.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. За период с января 2012 г. по январь 2025 г. в условиях ФГБУ «НМИЦ ДГОИ им. Дмитрия Рогачева» Минздрава России на базе патологоанатомического отделения зарегистрирован 1 случай с подтвержденным морфологическим диагнозом ЮГКО почки.</p></sec><sec><title>Результаты</title><p>Результаты. У девочки 11 лет отмечалось появление головной боли, тенденции к артериальной гипертензии (артериальное давление 170/90 мм рт. ст.). Жалобы сохранялись в течение 3 мес. Проведенное обследование (ультразвуковое исследование органов брюшной полости) выявило образование в проекции левой почки.</p><p>В результате дообследования в условиях НМИЦ ДГОИ им. Дмитрия Рогачева по данным мультиспиральной компьютерной томографии брюшной полости с внутривенным контрастированием отмечалась картина солидного образования неоднородной структуры в области среднего сегмента левой почки, размерами 3,2 × 2,9 × 3,0 см (V = 14,5 см3). По данным мультиспиральной компьютерной томографии органов грудной клетки с контрастированием метастатических изменений в легких не выявлено.</p><p>Учитывая клинико-рентгенологические данные, возраст пациентки (11 лет), небольшой объем образования (менее 200 см3), принято решение о проведении инициальной органосохраняющей операции. Проведена лапароскопическая резекция левой почки с выполнением биопсии забрюшинных лимфатических узлов.</p><p>По данным морфологического исследования у пациентки установлен морфологический диагноз: ЮГКО почки. Хирургическое вмешательство проведено радикально. В послеоперационном периоде отмечено купирование артериальной гипертензии.</p></sec><sec><title>Выводы</title><p>Выводы. Установление диагноза ЮГКО и определение тактики терапии требуют мультидисциплинарного подхода, при котором необходимо учитывать данные клинической картины и лабораторных показателей, а также опыт детских онкологов, специалистов лучевой диагностики, хирургической бригады и врачей-патологоанатомов. Небольшие размеры опухоли и доброкачественное течение позволяют рассматривать вопрос о проведении органосохраняющих операций, являющихся куративным методом терапии ЮГКО почек.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Background</title><p>Background. The juxtaglomerular cell tumor (JCT) of the kidney, or reninoma, is a rare benign renal neoplasm that occurs exceptionally rarely in pediatric patients. In contrast to other renal tumors, JCT pathogenesis is driven by renin-angiotensin system activation, clinically manifesting as refractory hypertension due to excessive tumor-derived renin secretion. We present a clinical case of an 11-year-old patient with JCT.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. From January 2012 to January 2025 in the Pathology Department of the Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology only one case of JCT was identified.</p></sec><sec><title>Results</title><p>Results. An 11-year-old girl had headaches and developed arterial hypertension (blood pressure 170/90 mmHg) during 3 months. Abdominal ultrasound revealed a tumor in the left kidney.</p><p>Further evaluation at the Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology showed contrast-enhanced abdominal computed tomography demonstrated a solid, heterogeneous mass (3.2 × 2.9 × 3.0 cm, V = 14.5 cm3) in the midsegment of the left kidney. There were no metastatic lung lesions on contrast-enhanced chest computed tomography.</p><p>According to the clinical-radiological findings, patient's age (11 years), and tumor characteristics (size &lt; 200 cm3), nephron-sparing surgery was performed. The patient underwent initial laparoscopic left kidney resection with lymph node sampling.</p><p>Histopathological examination confirmed the diagnosis of JCT and radical tumor resection. Arterial hypertension was relieved in the postoperative period.</p></sec><sec><title>Conclusions</title><p>Conclusions. The diagnosis and management of JCT require a multidisciplinary approach integrating clinical presentation, laboratory parameters, and expertise from pediatric oncologists, radiologists, surgeons, and pathologists. Given the tumor's typically small dimensions and benign biological behavior nephron-sparing surgery should be discussed with curative intent. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>юкстагломерулярноклеточная опухоль почки</kwd><kwd>дети</kwd><kwd>артериальная гипертензия</kwd><kwd>резекция почки</kwd></kwd-group><kwd-group xml:lang="en"><kwd>juxtaglomerular cell tumor</kwd><kwd>children</kwd><kwd>arterial hypertension</kwd><kwd>nephron-sparing surgery</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Shao L., Manalang M., Cooley L. Juxtaglomerular cell tumor in an 8-year-old girl. 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