nodgoРоссийский журнал детской гематологии и онкологии (РЖДГиО)Russian Journal of Pediatric Hematology and Oncology2311-12672413-5496LTD “Graphica”10.17650/2311-1267-2018-5-3-13-22nodgo-402Research ArticleИЗБРАННЫЕ ЛЕКЦИИSELECTED LECTURESНовые представления о свертывании кровиNew insights into the blood clottingАтауллахановФ. И.AtaullakhanovF. I.

Фазоил Иноятович Атауллаханов.

117997, Москва, ул. Саморы Машела, 1; 119992, Москва, ул. Ленинские Горы, 1, стр. 2; 119991, Москва, ул. Косыгина, 4

1 Samory Mashela St., Moscow, 117997; 1, Bldg. 2 Leninskie Gory St., Moscow, 119992; 4 Kosygina St., Moscow, 119991

ataullakhanov.fazly@gmail.comРумянцевА. Г.RumyantsevA. G.

117997, Москва, ул. Саморы Машела, 1; 117997, Москва, ул. Островитянова, 1

1 Samory Mashela St., Moscow, 117997; 1 Ostrovityanova St., Moscow, 117997

ФГБУ «Национальный медицинский исследовательский центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева» Минздрава России; ФГБОУ ВО «Московский государственный университет им. М.В. Ломоносова»; ФГБУН «Центр теоретических проблем физико-химической фармакологии» Российской академии наукРоссияDmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Ministry of Health of Russia; Lomonosov Moscow State University; Center for Theoretical Problems of Physicochemical PharmacologyRussian FederationФГБУ «Национальный медицинский исследовательский центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева» Минздрава России; ФГБОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава РоссииРоссияDmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Ministry of Health of Russia; N.I. Pirogov Russian National Research Medical University, Ministry of Health of RussiaRussian Federation201814092018531322Copyright © Атауллаханов Ф.И., Румянцев А.Г., 20182018Атауллаханов Ф.И., Румянцев А.Г.Ataullakhanov F.I., Rumyantsev A.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.nodgo.org/jour/article/view/402

В последние годы идет активный пересмотр представлений о механизмах свертывания крови. Традиционные представления во многом оказались неточны, что является главной причиной несостоятельности традиционной коагулограммы. Набор общепринятых методов оценки состояния гемостаза оказался малочувствителен, особенно к гиперкоагуляционным нарушениям. В данной работе рассматриваются современные представления о том, как происходит свертывание крови. Из этого рассмотрения вытекает необходимость критического пересмотра существующих методов оценки состояния гемостаза и стандартной коагулограммы. Лекция заканчивается кратким рассмотрением того, какой набор методов представляется на сегодня наиболее информативным и мог бы лечь в основу новой коагулограммы.

In recent years, an active revision of ideas about the mechanisms of blood clotting has been performed. Traditional views were largely inaccurate, which is the main reason for the inconsistency of the modern standard set of coagulation tests. This set was found to be insensitive, especially to hypercoagulable disorders. In this paper, we consider modern concepts of how blood clotting occurs. From this consideration follows the need for a critical review of existing methods for assessing the status of hemostasis and a standard set of laboratory tests. The lecture ends with a brief examination of which methods are the most informative today and could form the basis of a new informative coagulation testing set.

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The authors declare that there are no conflicts of interest present.