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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nodgo</journal-id><journal-title-group><journal-title xml:lang="ru">Российский журнал детской гематологии и онкологии (РЖДГиО)</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Pediatric Hematology and Oncology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2311-1267</issn><issn pub-type="epub">2413-5496</issn><publisher><publisher-name>LTD “Graphica”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21682/2311-1267-2019-6-3-31-43</article-id><article-id custom-type="elpub" pub-id-type="custom">nodgo-524</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Факторы риска по данным визуализации у пациентов с нейробластомой. Обзор литературы</article-title><trans-title-group xml:lang="en"><trans-title>Image defined risk factors in patients with neuroblastoma. Literature review</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9426-0676</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Терновая</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Ternovaya</surname><given-names>E. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Екатерина Сергеевна Терновая</p><p>врач рентгенологического отделения</p><p>117997, Москва, ул. Саморы Машела, 1</p></bio><bio xml:lang="en"><p>Physician of Radiology Department</p><p>1 Samory Mashela St., Moscow, 117997</p></bio><email xlink:type="simple">ekaterina.ternovaya@fccho-moscow.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3704-8783</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Качанов</surname><given-names>Д. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Kachanov</surname><given-names>D. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., заведующий отделением клинической онкологии, заместитель директора Института онкологии, радиологиии ядерной медицины, SPIN-код: 9878-5540</p><p>117997, Москва, ул. Саморы Машела, 1</p></bio><bio xml:lang="en"><p>Dr. of Sci. (Med.), Head of the Department of Clinical Oncology, Deputy Director of the Institute of Oncology, Radiology and Nuclear Medicine</p><p>1 Samory Mashela St., Moscow, 117997</p></bio><email xlink:type="simple">denis.kachanov@fccho-moscow.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3767-4477</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шаманская</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shamanskaya</surname><given-names>T. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., ученый секретарь Института онкологии, радиологии и ядерной медицины</p><p>117997, Москва, ул. Саморы Машела, 1</p></bio><bio xml:lang="en"><p>Cand. of Sci. (Med.), Scientific Secretary of the Institute of Oncology, Radiology and Nuclear Medicine</p><p>1 Samory Mashela St., Moscow, 117997</p></bio><email xlink:type="simple">shamanskaya.tatyana@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8129-0545</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Щербаков</surname><given-names>А. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Shcherbakov</surname><given-names>A. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач рентгенологического отделения НМИЦ ДГОИ им. Дмитрия Рогачева</p><p>117997, Москва, ул. Саморы Машела, 1</p></bio><bio xml:lang="en"><p>Physician of Radiology Department</p><p>1 Samory Mashela St., Moscow, 117997</p></bio><email xlink:type="simple">Alexey.Shcherbakov@fccho-moscow.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6131-1783</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Варфоломеева</surname><given-names>С. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Varfolomeeva</surname><given-names>S. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, заместитель директора по научной и лечебной работе – директор;</p><p>исполнительный директор РОО НОДГО;</p><p>115478, Москва, Каширское шоссе, 23</p></bio><bio xml:lang="en"><p>Dr. of Sci. (Med.), Professor, Deputy Director for Research and Clinical Work – Director, Executive Director of Regional Public Organization National Society of Pediatric Hematologists and Oncologists</p><p>23 Kashirskoe Shosse, Moscow, 115478</p></bio><email xlink:type="simple">clinoncology@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рубцова</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Rubtsova</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., руководитель отдела лучевой диагностики</p><p>125284, Москва, 2-й Боткинский пр., 3</p></bio><bio xml:lang="en"><p>Dr. of Sci. (Med.), Head of the Department Radiation Diagnosis</p><p>3 2nd Botkinskiy Proezd,Moscow, 125284</p></bio><email xlink:type="simple">rna17@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7317-7104</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Терещенко</surname><given-names>Г. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Tereshchenko</surname><given-names>G. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., врач-рентгенолог, заведующая рентгенологическим отделением</p><p>117997, Москва, ул. Саморы Машела, 1</p></bio><bio xml:lang="en"><p>Cand. of Sci. (Med.), Radiologist, Head of the Radiology Department</p><p>1 Samory Mashela St., Moscow, 117997</p></bio><email xlink:type="simple">galina.tereshenko@fccho-moscow.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «НМИЦ ДГОИ им. Дмитрия Рогачева» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>НИИ детской онкологии и гематологии ФГБУ «НМИЦ онкологии им. Н.Н. Блохина» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institute of Pediatric Oncology and Hematology of N.N. Blokhin National&#13;
Medical Research Centre of Oncology, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Московский научно-исследовательский онкологический институт им. П.А. Герцена – филиал ФГБУ «НМИЦ радиологии» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Center of Radiology, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>22</day><month>09</month><year>2019</year></pub-date><volume>6</volume><issue>3</issue><fpage>31</fpage><lpage>43</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Терновая Е.С., Качанов Д.Ю., Шаманская Т.В., Щербаков А.П., Варфоломеева С.Р., Рубцова Н.А., Терещенко Г.В., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Терновая Е.С., Качанов Д.Ю., Шаманская Т.В., Щербаков А.П., Варфоломеева С.Р., Рубцова Н.А., Терещенко Г.В.</copyright-holder><copyright-holder xml:lang="en">Ternovaya E.S., Kachanov D.Y., Shamanskaya T.V., Shcherbakov A.P., Varfolomeeva S.R., Rubtsova N.A., Tereshchenko G.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nodgo.org/jour/article/view/524">https://journal.nodgo.org/jour/article/view/524</self-uri><abstract><p>В настоящее время используются 2 системы стадирования пациентов с нейробластомой (НБ): Международная система стадирования НБ (INSS), которая опирается на данные хирургического этапа лечения, и Международная система стадирования групп риска НБ (INRGSS), которая основывается на данных предоперационной визуализации пациентов и выявляемых факторах риска. В статье представлен обзор литературы, посвященный данным факторам риска, методам их диагностики (компьютерной и магнитно-резонансной томографии) у пациентов с НБ, методике их описания, распространенности на этапе первичной диагностики и влиянию на результаты хирургического лечения и прогноз заболевания.</p></abstract><trans-abstract xml:lang="en"><p>Currently, two staging systems are used: the International Neuroblastoma Staging System (INSS), which relies on surgical staging, and the International Neroblastoma Risk Group Stading System (INRGSS), which relies on preoperative imaging for staging and image-defined risk. The article presents a review of the literature on image defined risk factors (IDRF) determined during radiological studies (computed tomography and magnetic resonance imaging) in patients with neuroblastoma. The article focuses on the definition of IDRFs, their prevalence and their influence on surgical outcomes and prognosis of patients with neuroblastoma.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>нейробластома</kwd><kwd>факторы риска по данным визуализации</kwd><kwd>дети</kwd><kwd>INSS</kwd><kwd>INRGSS</kwd></kwd-group><kwd-group xml:lang="en"><kwd>neuroblastoma</kwd><kwd>image defined risk factors</kwd><kwd>children</kwd><kwd>INSS</kwd><kwd>INRGSS</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Miller R.W., Young J.L. Jr., Novakovic B. Childhood cancer. Cancer 1995;75(1 Suppl):395–405. doi: 10.1002/1097-0142(19950101)75:1+&lt;395::aid-cncr2820751321&gt;3.0.co;2-w.</mixed-citation><mixed-citation xml:lang="en">Miller R.W., Young J.L. Jr., Novakovic B. Childhood cancer. 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