nodgoРоссийский журнал детской гематологии и онкологии (РЖДГиО)Russian Journal of Pediatric Hematology and Oncology2311-12672413-5496LTD “Graphica”10.21682/2311-1267-2019-6-4-93-96nodgo-559Research ArticleКЛИНИЧЕСКИЕ НАБЛЮДЕНИЯCLINICAL CASESБилатеральная лейомиома надпочечников: редкий случай и дифференциальная диагностика с точки зрения рентгенологаBilateral adrenal leiomyoma: a rare case and differential diagnosis from the point of view of the radiologisthttps://orcid.org/0000-0003-4164-004XСтрумилаН. А.StrumilaN. A.

Наталия Алексеевна Струмила - врач-рентгенолог, лаборант-исследователь отдела лучевой диагностики НМИЦ ДГОИ им. Дмитрия Рогачева.

117997, Москва, ул. Саморы Машела, 1

Research Assistant of Department Radiation Diagnosis.

1 Samory Mashela St., Moscow, 117997

natalya.strumila@fccho-moscow.ruhttps://orcid.org/0000-0003-1099-9332КрасновА. С.KrasnovA. S.

Врач-рентгенолог, научный сотрудник отдела лучевой диагностики НМИЦ ДГОИ им. Дмитрия Рогачева.

117997, Москва, ул. Саморы Машела, 1

Researcher of Department Radiation Diagnosis.

alexey.krasnov@fccho-moscow.ruhttps://orcid.org/0000-0001-7317-7104ТерещенкоГ. В.TereshchenkoG. V.

Кандидат медицинских наук, заведующая рентгенологическим отделением НМИЦ ДГОИ им. Дмитрия Рогачева.

117997, Москва, ул. Саморы Машела, 1

Cand. of Sci. (Med.), Head of Radiology Department.

1 Samory Mashela St., Moscow, 117997

Galina.Tereshenko@fccho-moscow.iuФГБУ «НМИЦДГОИ им. Дмитрия Рогачева» Минздрава РоссииРоссияDmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Ministry of Health of RussiaRussian Federation201922012020649396Copyright © Струмила Н.А., Краснов А.С., Терещенко Г.В., 20202020Струмила Н.А., Краснов А.С., Терещенко Г.В.Strumila N.A., Krasnov A.S., Tereshchenko G.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.nodgo.org/jour/article/view/559

Лейомиома — доброкачественная опухоль гладкомышечных клеток. Локализация данного образования в надпочечниках является крайне редкой, еще реже встречается поражение обоих надпочечников. В литературе нами было найдено менее 10 описанных случаев возникновения подобной патологии у детей. В статье представлен случай 17-летней девушки с жалобами на тахикардию и повышение давления, у которой впоследствии были выявлены билатеральные образования надпочечников. При гистологической верификации был установлен диагноз лейомиомы.

Leiomyoma is a benign tumor of smooth muscle cells. Localization of this formation in the adrenal glands is extremely rare, even less common is the defeat of both adrenal glands. In the literature, we found less than 10 described cases of the occurrence of a similar pathology in children. The article presents a case of a 17-year-old girl with complaints of tachycardia and an increase in pressure, which subsequently revealed bilateral adrenal masses. Histological verification diagnosed leiomyoma.

образование надпочечникакомпьютерная томографиямагнитно-резонансная томографиядетская онкологиядоброкачественная опухольadrenal gland masscomputed tomographymagnetic resonance imagingpediatric oncologybenign tumorReferencesHo Y.H., Yap W.M., Chuah K.L. Solitary fibrous tumor of the adrenal gland with unusual immunophenotype: a potential diagnostic problem and a brief review of endocrine organ solitary fibrous tumor. Endocr Pathol 2010;21(2):125-9. doi: m.m07/s12022-010-9113-z.Ho Y.H., Yap W.M., Chuah K.L. Solitary fibrous tumor of the adrenal gland with unusual immunophenotype: a potential diagnostic problem and a brief review of endocrine organ solitary fibrous tumor. Endocr Pathol 2010;21(2):125-9. doi: m.m07/s12022-010-9113-z.Corti M., Carolis L.D., Veliz L., Campitelli A., Haab G.A. Adrenal Leiomyoma: A Rare Tumor Presented as an Incidentaloma in a Patient with AIDS. Mathews J HIV AIDS 2016;1(1):006.Corti M., Carolis L.D., Veliz L., Campitelli A., Haab G.A. Adrenal Leiomyoma: A Rare Tumor Presented as an Incidentaloma in a Patient with AIDS. Mathews J HIV AIDS 2016;1(1):006.Lin J., Wasco M.J., Korobkin M., Doherty G., Giordano T.J. Leiomyoma of the adrenal gland presenting as a non-functioning adrenal incidentaloma: case report and review of the literature. Endocr Pathol 2007;18(4):239-43. doi: 10.1007/s12022-008-9013-7.Lin J., Wasco M.J., Korobkin M., Doherty G., Giordano T.J. Leiomyoma of the adrenal gland presenting as a non-functioning adrenal incidentaloma: case report and review of the literature. Endocr Pathol 2007;18(4):239-43. doi: 10.1007/s12022-008-9013-7.Lack E. Smooth muscle neoplasms. AFIP Atlas of Tumor Pathology, Tumors of the Adrenal Glands and Extraadrenal Paraganglia. Fourth Series. Fascicle, 2007.Lack E. Smooth muscle neoplasms. AFIP Atlas of Tumor Pathology, Tumors of the Adrenal Glands and Extraadrenal Paraganglia. Fourth Series. Fascicle, 2007.Huei T.J., Lip H.T.C., Rahman M., Arulanantham S. Large adrenal leiomyoma presented as adrenal incidentaloma in an AIDS patient: a rare entity. Med J Malaysia 2017;72(1):65-7. PMID: 28255146.Huei T.J., Lip H.T.C., Rahman M., Arulanantham S. Large adrenal leiomyoma presented as adrenal incidentaloma in an AIDS patient: a rare entity. Med J Malaysia 2017;72(1):65-7. PMID: 28255146.Rha S.E., Byun J.Y., Jung S.E., Chun H.J., Lee H.G., Lee J.M. Neurogenic tumors in the abdomen: tumor types and imaging characteristics. Radiographics 2003;23(1):29-43. doi: 10.1148/rg.231025050.Rha S.E., Byun J.Y., Jung S.E., Chun H.J., Lee H.G., Lee J.M. Neurogenic tumors in the abdomen: tumor types and imaging characteristics. Radiographics 2003;23(1):29-43. doi: 10.1148/rg.231025050.Lonergan G.J., Schwab C.M., Suarez E.S., Carlson C.L. From the archives of the AFIP: neuroblastoma, ganglioneuroblastoma, and ganglioneuroma: radiologic-pathologic correlation. Radiographics 2002;22(4):911-34. doi: 10.1148/radiographics.22.4.g02jl15911.Lonergan G.J., Schwab C.M., Suarez E.S., Carlson C.L. From the archives of the AFIP: neuroblastoma, ganglioneuroblastoma, and ganglioneuroma: radiologic-pathologic correlation. Radiographics 2002;22(4):911-34. doi: 10.1148/radiographics.22.4.g02jl15911.Pages P.M., Dufour C., Fasola S., Michon J., Boutard P., Gentet J.C., Hartmann O. Bilateral adrenal neuroblastoma. Pediatr Blood Cancer 2009;52(2):196-202. doi: 10.1002/pbc.21765.Pages P.M., Dufour C., Fasola S., Michon J., Boutard P., Gentet J.C., Hartmann O. Bilateral adrenal neuroblastoma. Pediatr Blood Cancer 2009;52(2):196-202. doi: 10.1002/pbc.21765.Papaioannou G., McHugh K. Neuroblastoma in childhood: review and radiological findings. Cancer Imaging 2005;5(1):116-27. doi: 10.1102/1470-7330.2005.0104.Papaioannou G., McHugh K. Neuroblastoma in childhood: review and radiological findings. Cancer Imaging 2005;5(1):116-27. doi: 10.1102/1470-7330.2005.0104.Blake M.A., Kalra M.K., Maher M.M., Sahani D.V., Sweeney A.T., Mueller P.R., Boland G.W. Pheochromocytoma: an imaging chameleon. Radiographics 2004;Suppl 1:S87-99. doi: 10.1148/rg.24si045506.Blake M.A., Kalra M.K., Maher M.M., Sahani D.V., Sweeney A.T., Mueller P.R., Boland G.W. Pheochromocytoma: an imaging chameleon. Radiographics 2004;Suppl 1:S87-99. doi: 10.1148/rg.24si045506.Sarathi V. Characteristics of Pediatric Pheochromocytoma/ paraganglioma. Indian J Endocrinol Metab 2017;21(3):470-4. doi: 10.4103/ijem.IJEM_558_16.Sarathi V. Characteristics of Pediatric Pheochromocytoma/ paraganglioma. Indian J Endocrinol Metab 2017;21(3):470-4. doi: 10.4103/ijem.IJEM_558_16.Prabhu M., Joseph T.T., Shetty N., Chaudhuri S. Saudi J Anaesth 2013;7(2):197-9. doi: 10.4103/1658-354X.114051.Prabhu M., Joseph T.T., Shetty N., Chaudhuri S. Saudi J Anaesth 2013;7(2):197-9. doi: 10.4103/1658-354X.114051.Johnson P.T., Horton K.M., Fishman E.K. Adrenal mass imaging with multidetector CT: pathologic conditions, pearls, and pitfalls. Radiographics 2009;29(5):1333-51. doi: 10.1148/rg.295095027.Johnson P.T., Horton K.M., Fishman E.K. Adrenal mass imaging with multidetector CT: pathologic conditions, pearls, and pitfalls. Radiographics 2009;29(5):1333-51. doi: 10.1148/rg.295095027.Mouchet F., Ninane J., Gosseye S., Verellen C., Bonnier C., Evrard P., Cornu G. Leiomyoma of the suprarenal gland in a child with ataxiatelangiectasia. Pediatr Hematol Oncol 1991;8(3):235-41. doi: 10.3109/08880019109033457.Mouchet F., Ninane J., Gosseye S., Verellen C., Bonnier C., Evrard P., Cornu G. Leiomyoma of the suprarenal gland in a child with ataxiatelangiectasia. Pediatr Hematol Oncol 1991;8(3):235-41. doi: 10.3109/08880019109033457.Jimenez-Heffernan J.A., Hardisson D., Palacios J., Garcia-Viera M., Gamallo C., Nistal M. Adrenal gland leiomyoma in a child with acquired immunodeficiency syndrome. Pediatr Pathol Lab Med 1995;15(6):923-9. doi: 10.3109/15513819509027028.Jimenez-Heffernan J.A., Hardisson D., Palacios J., Garcia-Viera M., Gamallo C., Nistal M. Adrenal gland leiomyoma in a child with acquired immunodeficiency syndrome. Pediatr Pathol Lab Med 1995;15(6):923-9. doi: 10.3109/15513819509027028.Demirel §., Erk O., Akkaya V., Tunaci A., Tanakol R., Terzioglu T., §enkal O. Multiple vascular leiomyomas involving bilateral adrenal glands, spleen, and epicardium, associated with bilateral testicular microlithiasis and empty sella turcica. J Pediatr Surg 1997;32(9): 1365-7. doi: 10.1016/s0022-3468(97)90324-9.Demirel §., Erk O., Akkaya V., Tunaci A., Tanakol R., Terzioglu T., §enkal O. Multiple vascular leiomyomas involving bilateral adrenal glands, spleen, and epicardium, associated with bilateral testicular microlithiasis and empty sella turcica. J Pediatr Surg 1997;32(9): 1365-7. doi: 10.1016/s0022-3468(97)90324-9.Rosenfeld D.L., Girgis W.S., Underberg-Davis S.J. Bilateral smooth-muscle tumors of the adrenals in a child with AIDS. Pediatr Radiol 1999;29(5):376-8. doi: 10.1007/s002470050611.Rosenfeld D.L., Girgis W.S., Underberg-Davis S.J. Bilateral smooth-muscle tumors of the adrenals in a child with AIDS. Pediatr Radiol 1999;29(5):376-8. doi: 10.1007/s002470050611.Chura J.C., Truskinovsky A.M., Judson P.L., Johnson L., Geller M.A., Downs L.S. Jr. Positron emission tomography and leiomyomas: clinicopathologic analysis of 3 cases of PET scan-positive leiomyomas and literature review. Gynecol Oncol 2007;104(1):247-52. doi: 10.1016/j.ygyno.2006.09.024.Chura J.C., Truskinovsky A.M., Judson P.L., Johnson L., Geller M.A., Downs L.S. Jr. Positron emission tomography and leiomyomas: clinicopathologic analysis of 3 cases of PET scan-positive leiomyomas and literature review. Gynecol Oncol 2007;104(1):247-52. doi: 10.1016/j.ygyno.2006.09.024.Parelkar S.V., Sampat N.P., Sanghvi B.V., Joshi P.B., Sahoo S.K., Patel J.L., Oak S.N. Case report of bilateral adrenal leiomyoma with review of literature. Pediatr Surg Int 2013;29(6):655-8. doi: 10.1007/s00383-013-3264-1.Parelkar S.V., Sampat N.P., Sanghvi B.V., Joshi P.B., Sahoo S.K., Patel J.L., Oak S.N. Case report of bilateral adrenal leiomyoma with review of literature. Pediatr Surg Int 2013;29(6):655-8. doi: 10.1007/s00383-013-3264-1.Monforte-Munoz H., Kapoor N., Saavedra J.A. Epstein-Barr virus-associated leiomyomatosis and posttransplant lymphoproliferative disorder in a child with severe combined immunodeficiency: case report and review of the literature. Pediatr Dev Pathol 2003;6(5):449-57. doi: 10.1007/s10024-003-8096-x.Monforte-Munoz H., Kapoor N., Saavedra J.A. Epstein-Barr virus-associated leiomyomatosis and posttransplant lymphoproliferative disorder in a child with severe combined immunodeficiency: case report and review of the literature. Pediatr Dev Pathol 2003;6(5):449-57. doi: 10.1007/s10024-003-8096-x.Arleo E.K., Schwartz P.E., Hui P., McCarthy S. Review of leiomyoma variants. AJR Am J Roentgenol 2015;205(4):912-21. doi: 10.2214/AJR.14.13946.Arleo E.K., Schwartz P.E., Hui P., McCarthy S. Review of leiomyoma variants. AJR Am J Roentgenol 2015;205(4):912-21. doi: 10.2214/AJR.14.13946.Kumar S., Nanjappa B., Agrawal P., Pushkarna A. Large bilateral adrenal leiomyomas presenting as calcified adrenal masses: a rare case report. Korean J Urol 2014;55(5):363-6. doi: 10.4111/kju.2014.55.5.363.Kumar S., Nanjappa B., Agrawal P., Pushkarna A. Large bilateral adrenal leiomyomas presenting as calcified adrenal masses: a rare case report. Korean J Urol 2014;55(5):363-6. doi: 10.4111/kju.2014.55.5.363.Alvarez S., McCabe W.R. Extrapulmonary tuberculosis revisited: a review of experience at Boston City and other hospitals. Medicine (Baltimore) 1984;63(1):25-55. PMID: 6419006.Alvarez S., McCabe W.R. Extrapulmonary tuberculosis revisited: a review of experience at Boston City and other hospitals. Medicine (Baltimore) 1984;63(1):25-55. PMID: 6419006.Lam K.Y., Lo C.Y. A critical examination of adrenal tuberculosis and a 28-year autopsy experience of active tuberculosis. Clin Endocrinol (Oxf) 2001;54(5):633-9. doi: 10.1046/j.1365-2265.2001.01266.x.Lam K.Y., Lo C.Y. A critical examination of adrenal tuberculosis and a 28-year autopsy experience of active tuberculosis. Clin Endocrinol (Oxf) 2001;54(5):633-9. doi: 10.1046/j.1365-2265.2001.01266.x.Vinnard C., Blumberg E.A. Endocrine and Metabolic Aspects of Tuberculosis. Microbiol Spectr 2017;5(1). doi: 10.1128/microbiolspec.TNMI7-0035-2016.Vinnard C., Blumberg E.A. Endocrine and Metabolic Aspects of Tuberculosis. Microbiol Spectr 2017;5(1). doi: 10.1128/microbiolspec.TNMI7-0035-2016.

The authors declare that there are no conflicts of interest present.