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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nodgo</journal-id><journal-title-group><journal-title xml:lang="ru">Российский журнал детской гематологии и онкологии (РЖДГиО)</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Pediatric Hematology and Oncology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2311-1267</issn><issn pub-type="epub">2413-5496</issn><publisher><publisher-name>LTD “Graphica”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21682/2311-1267-2020-7-4-82-85</article-id><article-id custom-type="elpub" pub-id-type="custom">nodgo-672</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПРАКТИЧЕСКИЕ ВОПРОСЫ ДЕТСКОЙ ОНКОЛОГИИ-ГЕМАТОЛОГИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PRACTICAL QUESTIONS OF PEDIATRIC ONCOLOGY-HEMATOLOGY</subject></subj-group></article-categories><title-group><article-title>Органосохраняющие операции как приоритетное направление в комбинированном лечении пациентов с саркомами костей</article-title><trans-title-group xml:lang="en"><trans-title>Limb salvage surgery as a priority direction in the combined treatment of bone sarcomas</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дзампаев</surname><given-names>А. З.</given-names></name><name name-style="western" xml:lang="en"><surname>Dzampaev</surname><given-names>A. Z.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дзампаев Аслан Зелимханович - кандидат медицинских наук, заведующий отделением хирургическим № 3 отдела общей онкологии НИИ детской онкологии и гематологии НМИЦ онкологии им. Н.Н. Блохина.115478, Москва, Каширское шоссе, 23.</p></bio><bio xml:lang="en"><p>Cand. of Sci. (Med.), Head of Surgical Department № 3 of the Department of General Oncology Research Institute of Pediatric Oncology and Hematology of N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia.23 Kashirskoe Shosse, Moscow, 115478.</p></bio><email xlink:type="simple">dzampaev@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нисиченко</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Nisichenko</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кандидат медицинских наук, старший научный сотрудник отделения хирургического № 3 отдела общей онкологии НИИ детской онкологии и гематологии НМИЦ онкологии им. Н.Н. Блохина.115478, Москва, Каширское шоссе, 23.SPIN-код: 2597-1880</p></bio><bio xml:lang="en"><p>Cand. of Sci. (Med.), Senior Researcher of Surgical Department № 3 of the Department of General Oncology Research Institute of Pediatric Oncology and Hematology of N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia.23 Kashirskoe Shosse, Moscow, 115478.SPIN-code: 2597-1880</p></bio><email xlink:type="simple">nisichenko@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2839-5222</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хестанов</surname><given-names>Д. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Hestanov</surname><given-names>D. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кандидат медицинских наук, старший научный сотрудник отделения хирургического № 3 отдела общей онкологии НИИ детской онкологии и гематологии НМИЦ онкологии им. Н.Н. Блохина.115478, Москва, Каширское шоссе, 23.SPIN-код: 9756-1732</p></bio><bio xml:lang="en"><p>Cand. of Sci. (Med.), Senior Researcher of Surgical Department № 3 of the Department of General Oncology Research Institute of Pediatric Oncology and Hematology of N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia.23 Kashirskoe Shosse, Moscow, 115478.SPIN-code: 9756-1732</p></bio><email xlink:type="simple">hestanov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>НМИЦ онкологии им. Н.Н. Блохина Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>N.N. Blokhin National Medical Research Centre of Oncology, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>07</day><month>01</month><year>2021</year></pub-date><volume>7</volume><issue>4</issue><fpage>82</fpage><lpage>85</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Дзампаев А.З., Нисиченко Д.В., Хестанов Д.Б., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Дзампаев А.З., Нисиченко Д.В., Хестанов Д.Б.</copyright-holder><copyright-holder xml:lang="en">Dzampaev A.Z., Nisichenko D.V., Hestanov D.B.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nodgo.org/jour/article/view/672">https://journal.nodgo.org/jour/article/view/672</self-uri><abstract><p>В настоящее время приоритетным направлением в детской онкологии является органосохраняющее лечение. Достигнутые за последние годы успехи в химиотерапии злокачественных опухолей костей, совершенствование хирургической техники, а также внедрение в ортопедию новейших технологий позволяют значительно расширить показания к эндопротезированию. К особенностям эндопротезирования детского возраста следует отнести применение раздвижных эндопротезов типа non-invasive и minimally invasive, что в последующем позволяет производить поэтапную коррекцию длины конечности и избежать различных нарушений опорно-двигательного аппарата (укорочение конечности, деформация позвоночника), тем самым улучшая качество жизни пациентов. В некоторых случаях, например при локализации опухоли в области верхней конечности, оптимальным решением может служить применение аутологичных трансплантатов на микрососудистых анастомозах. При локализации опухоли в области костей таза использование имплантов, изготовленых посредством 3D-моgелирования, по нашему мнению, также является оптимальным решением.</p></abstract><trans-abstract xml:lang="en"><p>Currently a priority in children oncology is a limb salvage treatment. Achieved in recent years advances in chemotherapy of malignant bone tumors, improved surgical techniques, and also introduction in orthopedics of the newest technologies allow to considerably expand the indications for endoprosthesis. A feature in cases in children of early age is the use of sliding implants type non-invasive and minimally invasive that subsequently allows gradual correction of leg length and avoid the various disorders of musculoskeletal system (shortened limbs, spinal deformity), thereby improving the quality of life of patients. In some cases, for example, when a tumor is localized in the upper limb region, the optimal solution may be the use of autologous grafts on microvascular anastomoses. In the case of tumor localization in the pelvic region, the use of implants made by means of 3D-modeling, in our opinion, is also an optimal solution.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>эндопротезирование у детей</kwd><kwd>раздвижные (growing) эндопротезы</kwd><kwd>аутопластика</kwd><kwd>3D-импланты</kwd><kwd>лечение пациентов с саркомами длинных трубчатых костей</kwd></kwd-group><kwd-group xml:lang="en"><kwd>endoprosthesis in children</kwd><kwd>growing endoprosthesis</kwd><kwd>autoplasty</kwd><kwd>3D-implants</kwd><kwd>treatment of patients with sarcomas of long bones</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Abudu A., Grimer R., Tillman R., Carter S. The use of prostheses in skeletally immature patients. Orthop Clin North Am 2006;37(1):75-84. doi: 10.1016/j.ocl.2005.08.008.</mixed-citation><mixed-citation xml:lang="en">Abudu A., Grimer R., Tillman R., Carter S. The use of prostheses in skeletally immature patients. Orthop Clin North Am 2006;37(1):75-84. doi: 10.1016/j.ocl.2005.08.008.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Brown K.L. Resection, rotationplasty, and femoropelvic arthrodesis in severe congenital femoral deficiency. A report of the surgical technique and three cases. J Bone Joint Surg Am 2001;83(1):78-85. doi: 10.2106/00004623-200101000-00011.</mixed-citation><mixed-citation xml:lang="en">Brown K.L. Resection, rotationplasty, and femoropelvic arthrodesis in severe congenital femoral deficiency. A report of the surgical technique and three cases. J Bone Joint Surg Am 2001;83(1):78-85. doi: 10.2106/00004623-200101000-00011.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Dominkus M., Krepler P., Schwameis E., Windhager R., Kotz R. Growth prediction in extendable tumor prostheses in children. Clin Orthop Relat Res 2001;(390):212-20. doi: 10.1097/00003086-200109000-00024.</mixed-citation><mixed-citation xml:lang="en">Dominkus M., Krepler P., Schwameis E., Windhager R., Kotz R. Growth prediction in extendable tumor prostheses in children. Clin Orthop Relat Res 2001;(390):212-20. doi: 10.1097/00003086-200109000-00024.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Eckardt J.J., Kabo J.M., Kelley C.M., Ward W.G., Asavamongkolkul A., Wirganowicz P.Z., Yang R.S., Eilber F.R. Expandable endoprosthesis reconstruction in skeletally immature patients with tumors. Clin Orthop Relat Res 2000;(373):51-61. doi: 10.1097/00003086-200004000-00008.</mixed-citation><mixed-citation xml:lang="en">Eckardt J.J., Kabo J.M., Kelley C.M., Ward W.G., Asavamongkolkul A., Wirganowicz P.Z., Yang R.S., Eilber F.R. Expandable endoprosthesis reconstruction in skeletally immature patients with tumors. Clin Orthop Relat Res 2000;(373):51-61. doi: 10.1097/00003086-200004000-00008.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Enneking W.F., Dunham W., Gebhardt M.C., Malawar M., Pritchard D.J. A system for the functional evaluation of reconstructive procedures after surgical treatment of tumors of the musculoskeletal system. Clin Orthop Relat Res 1993;(286):241-6. PMID: 8425352.</mixed-citation><mixed-citation xml:lang="en">Enneking W.F., Dunham W., Gebhardt M.C., Malawar M., Pritchard D.J. A system for the functional evaluation of reconstructive procedures after surgical treatment of tumors of the musculoskeletal system. Clin Orthop Relat Res 1993;(286):241-6. PMID: 8425352.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Keohan M.L., Taub R.N. Chemotherapy for advanced sarcoma: therapeutic decisions and modalities. Semin Oncol 1997;24(5):572-9. PMID: 9344324.</mixed-citation><mixed-citation xml:lang="en">Keohan M.L., Taub R.N. Chemotherapy for advanced sarcoma: therapeutic decisions and modalities. Semin Oncol 1997;24(5):572-9. PMID: 9344324.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Letson G.D., D'Amato G., Windham T.C., Muro-Cacho C.A. Extendable prostheses for the treatment of malignant bone tumors in growing children. Curr Opin Orthop 2003;14:413-8. doi: 10.1097/00001433-200312000-00010.</mixed-citation><mixed-citation xml:lang="en">Letson G.D., D'Amato G., Windham T.C., Muro-Cacho C.A. Extendable prostheses for the treatment of malignant bone tumors in growing children. Curr Opin Orthop 2003;14:413-8. doi: 10.1097/00001433-200312000-00010.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Lewis V.O. Limb salvage in the skeletally immature patient. Curr Oncol Rep 2005;7(4):285-92. doi: 10.1007/s11912-005-0052-7.</mixed-citation><mixed-citation xml:lang="en">Lewis V.O. Limb salvage in the skeletally immature patient. Curr Oncol Rep 2005;7(4):285-92. doi: 10.1007/s11912-005-0052-7.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Malawer M. Surgical technique and results of limb sparing surgery for high grade bone sarcomas of the knee and shoulder. Orthopedics 1985;8(5):597-607. PMID: 3006004.</mixed-citation><mixed-citation xml:lang="en">Malawer M. Surgical technique and results of limb sparing surgery for high grade bone sarcomas of the knee and shoulder. Orthopedics 1985;8(5):597-607. PMID: 3006004.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Neel M.D., Letson G.D. Modular endoprostheses for children with malignant bone tumors. Cancer Control 2001;8(4):344-8. doi: 10.1177/107327480100800406.</mixed-citation><mixed-citation xml:lang="en">Neel M.D., Letson G.D. Modular endoprostheses for children with malignant bone tumors. Cancer Control 2001;8(4):344-8. doi: 10.1177/107327480100800406.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Simon M.A., Aschliman M.A., Thomas N., Mankin H.J. Limb-salvage treatment versus amputation for osteosarcoma of the distal end of the femur 1986. J Bone Joint Surg Am 2005;87(12):2822. doi: 10.2106/JBJS.8712.cl.</mixed-citation><mixed-citation xml:lang="en">Simon M.A., Aschliman M.A., Thomas N., Mankin H.J. Limb-salvage treatment versus amputation for osteosarcoma of the distal end of the femur 1986. J Bone Joint Surg Am 2005;87(12):2822. doi: 10.2106/JBJS.8712.cl.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Tillman R.M., Grimer R.J., Carter S.R., Cool W.P., Sneath R.S. Growing endoprostheses for primary malignant bone tumors. Semin Surg Oncol 1997;13(1):41-8. doi: 10.1002/(sici)1098-2388(199701/02)13:1&lt;41::aid-ssu7&gt;3.0.co;2-4.</mixed-citation><mixed-citation xml:lang="en">Tillman R.M., Grimer R.J., Carter S.R., Cool W.P., Sneath R.S. Growing endoprostheses for primary malignant bone tumors. Semin Surg Oncol 1997;13(1):41-8. doi: 10.1002/(sici)1098-2388(199701/02)13:1&lt;41::aid-ssu7&gt;3.0.co;2-4.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
