nodgoРоссийский журнал детской гематологии и онкологии (РЖДГиО)Russian Journal of Pediatric Hematology and Oncology2311-12672413-5496LTD “Graphica”10.21682/2311-1267-2021-8-2-96-102nodgo-727Research ArticleКЛИНИЧЕСКИЕ НАБЛЮДЕНИЯCLINICAL CASESЛапароскопическая резекция почки у ребенка с односторонней опухолью ВильмсаLaparoscopic kidney resection in a child with unilateral Wilms tumorhttps://orcid.org/0000-0003-3850-7109НосовА. К.NosovA. K.

Носов Александр Константинович - кандидат медицинских наук, заведующий хирургическим отделением онкоурологии и общей онкологии, старший научный сотрудник НМИЦ онкологии им. Н.Н. Петрова.

197758, Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68.

Cand. of Sci. (Med.), Head of the Surgical Department of Oncological Urology and General Oncology, Senior Researcher N.N. Petrov National Medical Research Center of Oncology, Ministry of Health of Russia.

68 Leningradskaya St., Pesochny, Saint Petersburg, 197758.

nakuro@yandex.ruhttps://orcid.org/0000-0003-0390-8498КулеваС. А.KulevaS. A.

Доктор медицинских наук, профессор, заведующая детским онкологическим отделением, ведущий научный сотрудник научного отдела инновационных методов терапевтической онкологии и реабилитации, профессор учебно-методического отдела НМИЦ онкологии им. Н.Н. Петрова, заведующая кафедрой онкологии, детской онкологии и лучевой терапии СПбГПМУ.

197758, Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68; 194100, Санкт-Петербург, ул. Литовская, 2.

SPIN-код: 3441-4820

Dr. of Sci. (Med.), Professor, Head of Pediatric Oncology Department, Leading Researcher of the Research Department of Innovative Therapeutic Oncology and Rehabilitation Methods, Professor of the Training and Methodology Department N.N. Petrov National Medical Research Center of Oncology, Ministry of Health of Russia, Head of Department of Oncology, Pediatric Oncology and Radiotherapy of the Saint-Petersburg State Pediatric Medical University, Ministry of Health of Russia.

68 Leningradskaya St., Pesochny, Saint Petersburg, 197758; 2 Litovskaya St., S.-Petersburg, 194100.

SPIN-code: 3441-4820

kulevadoc@yandex.ruhttps://orcid.org/0000-0002-0585-0907ИвановаС. В.IvanovaS. V.

Кандидат медицинских наук, врач-детский онколог детского онкологического отделения, научный сотрудник научного отдела инновационных методов терапевтической онкологии и реабилитации НМИЦ онкологии им. Н.Н. Петрова, доцент кафедры онкологии, детской онкологии и лучевой терапии СПбГПМУ.

197758, Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68; 194100, Санкт-Петербург, ул. Литовская, 2.

SPIN-код: 9442-5015

Cand. of Sci. (Med.), Pediatric Oncologist of Pediatric Oncology Department, Researcher of the Research Department of Innovative Therapeutic Oncology and Rehabilitation Methods N.N. Petrov National Medical Research Center of Oncology, Ministry of Health of Russia, Associate Professor of the Department of Oncology, Pediatric Oncology and Radiotherapy of the Saint-Petersburg State Pediatric Medical University, Ministry of Health of Russia.

68 Leningradskaya St., Pesochny, Saint Petersburg, 197758; 2 Litovskaya St., S.-Petersburg, 194100.

SPIN-code: 9442-5015

tabalinadoc@yandex.ruhttps://orcid.org/0000-0002-6742-5754СенчуровЕ. М.SenchurovE. M.

Врач-детский хирург, онколог детского онкологического отделения НМИЦ онкологии им. Н.Н. Петрова.

197758, Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68.

Pediatric Oncologist of Pediatric Oncology Department N.N. Petrov National Medical Research Center of Oncology, Ministry of Health of Russia.

68 Leningradskaya St., Pesochny, Saint Petersburg, 197758.

senchurov85@mail.ruhttps://orcid.org/0000-0002-6433-8487ХабароваР. И.KhabarovaR. I.

Врач-детский онколог детского онкологического отделения НМИЦ онкологии им. Н.Н. Петрова.

197758, Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68.

SPIN-код: 6824-8710

Pediatric Oncologist of Pediatric Oncology Department N.N. Petrov National Medical Research Center of Oncology, Ministry of Health of Russia.

68 Leningradskaya St., Pesochny, Saint Petersburg, 197758.

SPIN-code: 6824-8710

izmozherova@yandex.ruhttps://orcid.org/0000-0003-1081-5118МихайловаЕ. А.MikhailovaE. A.

Врач-детский онколог детского онкологического отделения НМИЦ онкологии им. Н.Н. Петрова.

197758, Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68.

SPIN-код: 2940-2186

Pediatric Oncologist of the Pediatric Oncology Department N.N. Petrov National Medical Research Center of Oncology, Ministry of Health of Russia.

68 Leningradskaya St., Pesochny, Saint Petersburg, 197758.

SPIN-code: 2940-2186

helen_mikhaylova@mail.ruЩекутеевН. А.ShchekuteevN. A.

Врач-уролог отделения онкоурологии и общей онкологии НМИЦ онкологии им. Н.Н. Петрова.

197758, Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68.

Urologist Surgical Department of Oncological Urology and General Oncology N.N. Petrov National Medical Research Center of Oncology, Ministry of Health of Russia.

68 Leningradskaya St., Pesochny, Saint Petersburg, 197758.

shhek-nikita@mail.ruhttps://orcid.org/0000-0002-5004-1543БорокшиноваК. М.BorokshinovaK. M.

Врач-детский онколог детского онкологического отделения НМИЦ онкологии им. Н.Н. Петрова.

197758, Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68.

Pediatric Oncologist of Pediatric Oncology Department N.N. Petrov National Medical Research Center of Oncology, Ministry of Health of Russia.

68 Leningradskaya St., Pesochny, Saint Petersburg, 197758.

bk0807@bk.ruhttps://orcid.org/0000-0002-0112-0579ГридасовВ. В.GridasovV. V.

Врач-рентгенолог отделения лучевой диагностики НМИЦ онкологии им. Н.Н. Петрова.

197758, Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68.

Radiologist of Radiology Department N.N. Petrov National Medical Research Center of Oncology, Ministry of Health of Russia.

68 Leningradskaya St., Pesochny, Saint Petersburg, 197758.

Mdgridasov@gmail.ruhttps://orcid.org/0000-0002-0551-804XХохловаА. В.KhokhlovaA. V.

Врач-патологоанатом патологоанатомического отделения с прозектурой НМИЦ онкологии им. Н.Н. Петрова.

197758, Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68.

SPIN-код: 9235-0099

Pathologist Department of Pathology N.N. Petrov National Medical Research Centre of Oncology, Ministry of Health of Russia.

68 Leningradskaya St., Pesochny, Saint Petersburg, 197758.

SPIN-code: 9235-0099

apatom666@gmail.comНациональный медицинский исследовательский центр онкологии имени Н.Н. Петрова» Минздрава РоссииРоссияN.N. Petrov National Medical Research Center of Oncology, Ministry of Health of RussiaRussian FederationНациональный медицинский исследовательский центр онкологии имени Н.Н. Петрова Минздрава России; СПбГПМУ Минздрава РоссииРоссияN.N. Petrov National Medical Research Center of Oncology, Ministry of Health of Russia; Saint-Petersburg State Pediatric Medical University, Ministry of Health of RussiaRussian Federation2021120720218296102Copyright © Носов А.К., Кулева С.А., Иванова С.В., Сенчуров Е.М., Хабарова Р.И., Михайлова Е.А., Щекутеев Н.А., Борокшинова К.М., Гридасов В.В., Хохлова А.В., 20212021Носов А.К., Кулева С.А., Иванова С.В., Сенчуров Е.М., Хабарова Р.И., Михайлова Е.А., Щекутеев Н.А., Борокшинова К.М., Гридасов В.В., Хохлова А.В.Nosov A.K., Kuleva S.A., Ivanova S.V., Senchurov E.M., Khabarova R.I., Mikhailova E.A., Shchekuteev N.A., Borokshinova K.M., Gridasov V.V., Khokhlova A.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.nodgo.org/jour/article/view/727

Современные протоколы лечения детей с опухолью Вильмса (ОВ), применяемые во всем мире, позволяют излечить до 90 % пациентов. Подобные успехи позволили активно вводить риск-адаптированные методики терапии, направленные на деэскалацию режимов полихимиотерапии и лучевого воздействия на опухоль. Наиболее консервативным оставался этап хирургического лечения, подразумевающий органоуносящий характер оперативного пособия. Тем не менее в последние десятилетия был накоплен опыт нефронсберегающих вмешательств, в том числе выполненных из лапароскопического доступа у больных с одно- и двусторонней нефробластомой.

Мы представляем опыт лапароскопической резекции почки с интраоперационным ультразвуковым контролем у ребенка с односторонней ОВ, получавшего лечение в НМИЦ онкологии им. Н.Н. Петрова.

The modern Wilms tumor treatment protocols used all over the world can cure up to 90 % of children. Such successes make it possible to actively introduce risk-adapted therapy methods aimed at de-escalating the chemotherapy regimen and radiation therapy impact to the tumor. The most conservative was the stage of surgical treatment, implying the organ-depleting nature of the surgery. Nevertheless, over the past decade, a lot of experience has been accumulated with both nephron-sparing and minimally invasive interventions in patients with both bilateral and unilateral Wilms tumor.

We presented the experience of laparoscopic kidney resection with intraoperative ultrasound control in a child with unilateral Wilms tumor, receiving treatment at the N.N. Petrov National Medical Research Center of Oncology.

детиопухоль Вильмсанефронсберегающая операциярезекция почкилапароскопияchildrenWilms tumornephron-sparing surgerykidney resectionlaparoscopyReferencesShamberger R.C., Guthrie K.A., Ritchey M.L., Haase G.M., Takashima J., Beckwith J.B., D’Angio G.J., Green D.M., Breslow N.E. Surgery-related factors and local recurrence of Wilms tumor in National Wilms Tumor Study 4. Ann Surg 1999;229(2):292-7. doi: 10.1097/00000658-199902000-00019.Shamberger R.C., Guthrie K.A., Ritchey M.L., Haase G.M., Takashima J., Beckwith J.B., D’Angio G.J., Green D.M., Breslow N.E. Surgery-related factors and local recurrence of Wilms tumor in National Wilms Tumor Study 4. Ann Surg 1999;229(2):292-7. doi: 10.1097/00000658-199902000-00019.Ritchey M.L., Green D.M., Thomas P.R., Smith G.R., Haase G., Shochat S., Moksness J., Breslow N.E. Renal failure in Wilms' tumor patients: a report from the National Wilms' Tumor Study Group. Medical and Pediatric Oncology 1996;26(2):75-80. doi: 10.1002/(sici)1096-911x(199602)26:2<75::aid-mpo1>3.0.co;2-r.Ritchey M.L., Green D.M., Thomas P.R., Smith G.R., Haase G., Shochat S., Moksness J., Breslow N.E. Renal failure in Wilms' tumor patients: a report from the National Wilms' Tumor Study Group. Medical and Pediatric Oncology 1996;26(2):75-80. doi: 10.1002/(sici)1096-911x(199602)26:2<75::aid-mpo1>3.0.co;2-r.Cozzi F., Schiavetti A. Letter to the editor: Nephron sparing surgery for unilateral Wilms' tumor. Med Pediatr Oncol 1997;28(3);239-40. doi: 10.1002/(sici)1096-911x(199703)28:3<239::aid-mpo18>3.0.co;2-9.Cozzi F., Schiavetti A. Letter to the editor: Nephron sparing surgery for unilateral Wilms' tumor. Med Pediatr Oncol 1997;28(3);239-40. doi: 10.1002/(sici)1096-911x(199703)28:3<239::aid-mpo18>3.0.co;2-9.Cherullo E.E., Ross J.H., Kay R., Novick A.C. Renal neoplasms in adult survivors of childhood Wilms tumor. J Urol 2001;165(6 Pt 1):2013-6; discussion 2016-7. doi: 10.1097/00005392-200106000-00059.Cherullo E.E., Ross J.H., Kay R., Novick A.C. Renal neoplasms in adult survivors of childhood Wilms tumor. J Urol 2001;165(6 Pt 1):2013-6; discussion 2016-7. doi: 10.1097/00005392-200106000-00059.Paulino A.C., Wen B.C., Brown C.K., Tannous R., Mayr N.A., Zhen W.K., Weidner G.J., Hussey D.H. Late effects in children treated with radiation therapy for Wilms' tumor. Int J Radiat Oncol Biol Phys 2000;46(5):1239-46. doi: 10.1016/s0360-3016(99)00534-9.Paulino A.C., Wen B.C., Brown C.K., Tannous R., Mayr N.A., Zhen W.K., Weidner G.J., Hussey D.H. Late effects in children treated with radiation therapy for Wilms' tumor. Int J Radiat Oncol Biol Phys 2000;46(5):1239-46. doi: 10.1016/s0360-3016(99)00534-9.Breslow N.E., Collins A.J., Ritchey M.L., Grigoriev Y.A., Peterson S.M., Green D.M. End stage renal disease in patients with Wilms tumor: results from the National Wilms Tumor Study Group and the United States Renal Data System. J Urol 2005;174(5):1972-5. doi: 10.1097/01.ju.0000176800.00994.3a.Breslow N.E., Collins A.J., Ritchey M.L., Grigoriev Y.A., Peterson S.M., Green D.M. End stage renal disease in patients with Wilms tumor: results from the National Wilms Tumor Study Group and the United States Renal Data System. J Urol 2005;174(5):1972-5. doi: 10.1097/01.ju.0000176800.00994.3a.Kern A.J.M., Inouye B., Ko J.S., Gorin M.A., Allaf M.E., Goldstein S., DiCarlo H.N., Shah B.B., Wang M.H. Impact of nephrectomy on longterm renal function in non-syndromic children treated for unifocal Wilms tumor. J Pediatr Urol 2014;10(4):662-6. doi: 10.1016/j.jpurol.2014.06.017.Kern A.J.M., Inouye B., Ko J.S., Gorin M.A., Allaf M.E., Goldstein S., DiCarlo H.N., Shah B.B., Wang M.H. Impact of nephrectomy on longterm renal function in non-syndromic children treated for unifocal Wilms tumor. J Pediatr Urol 2014;10(4):662-6. doi: 10.1016/j.jpurol.2014.06.017.Neu M.A., Russo A., Wingerter A., Alt F., Theruvath J., Malki E., Kron B., Dittrich M., Lotz J., Stein R., Beetz R., Faber J. Prospective analysis of long-term renal function in survivors of childhood Wilms tumor. Pediatr Nephrol 2017;32(10):1915-25. doi: 10.1007/s00467-017-3673-9.Neu M.A., Russo A., Wingerter A., Alt F., Theruvath J., Malki E., Kron B., Dittrich M., Lotz J., Stein R., Beetz R., Faber J. Prospective analysis of long-term renal function in survivors of childhood Wilms tumor. Pediatr Nephrol 2017;32(10):1915-25. doi: 10.1007/s00467-017-3673-9.Zani A., Schiavetti A., Gambino M., Cozzi D., Conforti A., Cozzi F. Long-term outcome of nephron sparing surgery and simple nephrectomy for unilateral localized Wilms Tumor. J Urol 2005;173(3):946-8. doi: 10.1097/01.ju.0000152580.90861.d3.Zani A., Schiavetti A., Gambino M., Cozzi D., Conforti A., Cozzi F. Long-term outcome of nephron sparing surgery and simple nephrectomy for unilateral localized Wilms Tumor. J Urol 2005;173(3):946-8. doi: 10.1097/01.ju.0000152580.90861.d3.Cost N.G., Lubahn J.D., Granberg C.F., Schlomer B.J., Wickiser J.E., Rakheja D., Gargollo P.C., Leonard D., Raj G.V., Baker L.A., Margulis V. Oncologic outcomes of partial versus radical nephrectomy for unilateral Wilms Tumor. Pediatr Blood Cancer 2011;58(6):898-904. doi: 10.1002/pbc.23240.Cost N.G., Lubahn J.D., Granberg C.F., Schlomer B.J., Wickiser J.E., Rakheja D., Gargollo P.C., Leonard D., Raj G.V., Baker L.A., Margulis V. Oncologic outcomes of partial versus radical nephrectomy for unilateral Wilms Tumor. Pediatr Blood Cancer 2011;58(6):898-904. doi: 10.1002/pbc.23240.Schiavetti A., Bonci E., Varrasso G., De Grazia A., Cozzi D.A. Evaluation of Nephron-Sparing Surgery as Potential Risk Factor for Relapse in Unilateral Wilms Tumor. J Surg Res 2019;247:21-7. doi: 10.1016/j.jss.2019.11.001.Schiavetti A., Bonci E., Varrasso G., De Grazia A., Cozzi D.A. Evaluation of Nephron-Sparing Surgery as Potential Risk Factor for Relapse in Unilateral Wilms Tumor. J Surg Res 2019;247:21-7. doi: 10.1016/j.jss.2019.11.001.Cozzi F., Schiavetti A., Morini F., Cozzi D.A. Re: partial nephrectomy for unilateral wilms tumor: results of study SIOP 93-01/GPOH. J Urol 2004;171(6 Pt 1):2383; author reply 2383. doi: 10.1097/01.ju.0000124464.67056.63.Cozzi F., Schiavetti A., Morini F., Cozzi D.A. Re: partial nephrectomy for unilateral wilms tumor: results of study SIOP 93-01/GPOH. J Urol 2004;171(6 Pt 1):2383; author reply 2383. doi: 10.1097/01.ju.0000124464.67056.63.Tricard T., Lacreuse I., Louis V., Schneider A., Chaussy Y., Soler L., Moog R., Lang H., Jacqmin D., Becmeur F. Is nephron-sparing surgery relevant for unilateral Wilms tumors. Arch Pediatr 2017;24(7):650-8. doi: 10.1016/j.arcped.2017.04.003.Tricard T., Lacreuse I., Louis V., Schneider A., Chaussy Y., Soler L., Moog R., Lang H., Jacqmin D., Becmeur F. Is nephron-sparing surgery relevant for unilateral Wilms tumors. Arch Pediatr 2017;24(7):650-8. doi: 10.1016/j.arcped.2017.04.003.Haecker F.M., Von Schweinitz D., Harms D., Buerger D., Graf N. Partial Nephrectomy for Unilateral Wilms Tumor: Results of Study. J Urol 2003;170(3):939-44. doi: 10.1097/01.ju.0000073848.33092.c7.Haecker F.M., Von Schweinitz D., Harms D., Buerger D., Graf N. Partial Nephrectomy for Unilateral Wilms Tumor: Results of Study. J Urol 2003;170(3):939-44. doi: 10.1097/01.ju.0000073848.33092.c7.Duarte R., Denes F., Cristofani L., Giron A., Filho V., Arap S. Laparoscopic nephrectomy for Wilms tumor after chemotherapy: initial experience. J Urol 2004;172(4):1438-40. doi: 10.1097/01.ju.0000138230.51134.65.Duarte R., Denes F., Cristofani L., Giron A., Filho V., Arap S. Laparoscopic nephrectomy for Wilms tumor after chemotherapy: initial experience. J Urol 2004;172(4):1438-40. doi: 10.1097/01.ju.0000138230.51134.65.Duarte R.J., Denes F.T., Cristofani L.M., Odone-Filho V., Srougi M. Further experience with laparoscopic nephrectomy for Wilms' tumour after chemotherapy. BJU Int 2006;98(1):155-9. doi: 10.1111/j.1464-410x.2006.06214.Duarte R.J., Denes F.T., Cristofani L.M., Odone-Filho V., Srougi M. Further experience with laparoscopic nephrectomy for Wilms' tumour after chemotherapy. BJU Int 2006;98(1):155-9. doi: 10.1111/j.1464-410x.2006.06214.Labanaris A.P., Krot D., Schott G.E., Zugor V. Further experience with laparoscopic nephrectomy for Wilms' tumour after chemotherapy. BJU Int 2006;98(4):919. doi: 10.1111/j.1464-410x.2006.06473_7.Labanaris A.P., Krot D., Schott G.E., Zugor V. Further experience with laparoscopic nephrectomy for Wilms' tumour after chemotherapy. BJU Int 2006;98(4):919. doi: 10.1111/j.1464-410x.2006.06473_7.Shanberg A.M., Perer E., Matsunaga G. Re: Laparoscopic Nephrectomy for Wilms Tumor After Chemotherapy: Initial Experience. J Urol 2006;175(2):788. doi: 10.1016/s0022-5347(05)00175-8.Shanberg A.M., Perer E., Matsunaga G. Re: Laparoscopic Nephrectomy for Wilms Tumor After Chemotherapy: Initial Experience. J Urol 2006;175(2):788. doi: 10.1016/s0022-5347(05)00175-8.Warmann S.W., Godzinski J., van Tinteren H., Heij H., Powis M., Sandstedt B., Graf N., Fuchs J. Minimally invasive nephrectomy for Wilms tumors in children. J Pediatr Surg 2014;49(11):1544-8. doi: 10.1016/j.jpedsurg.2014.06.005.Warmann S.W., Godzinski J., van Tinteren H., Heij H., Powis M., Sandstedt B., Graf N., Fuchs J. Minimally invasive nephrectomy for Wilms tumors in children. J Pediatr Surg 2014;49(11):1544-8. doi: 10.1016/j.jpedsurg.2014.06.005.Bouty A., Blanc T., Leclair M.D., Lavrand F., Faure A., Binet A., Rod J., O’Brien M., Sarnacki S., Nightingale M., Heloury Y., Varlet F., Scalabre A. Minimally invasive surgery for unilateral Wilms tumors: Multicenter retrospective analysis of 50 transperitoneal laparoscopic total nephrectomies. Pediatr Blood Cancer 2020;67(5):e28212. doi: 10.1002/pbc.28212.Bouty A., Blanc T., Leclair M.D., Lavrand F., Faure A., Binet A., Rod J., O’Brien M., Sarnacki S., Nightingale M., Heloury Y., Varlet F., Scalabre A. Minimally invasive surgery for unilateral Wilms tumors: Multicenter retrospective analysis of 50 transperitoneal laparoscopic total nephrectomies. Pediatr Blood Cancer 2020;67(5):e28212. doi: 10.1002/pbc.28212.Волобуев А. В., Рубанский М. А., Рубанская М.В., Казанцев А.П., Керимов П. А., Капкова О. А., Рыбакова Д. В., Рябов А. Б. Лапароскопические вмешательства при опухолях почек у детей. Материалы II съезда детских урологов-андрологов, 2011. С. 21.Volobuev A.V., Rubansky M.A., Rubanskaya M.V., Kazantsev A.P., Kerimov P.A., Kapkova O.A., Rybakova D.V., Ryabov A.B. Laparoscopic interventions for kidney tumors in children. Materials of the II Congress of Children's Urologists Andrologists, 2011. P. 21. (In Russ.).Каганцов И.М., Карманов А.Л., Сварич А.Г., Санников И.А. Лапароскопическая нефрэктомия у грудных детей с опухолью Вильм-са. Российский вестник детской хирургии, анестезиологии и реаниматологии 2018;8(3):53-9. doi: 10.30946/2219-4061-2018-8-3-53-59.Kagantsov I.M., Karmanov A.L., Svarich A.G., Sannikov I.A. Laparoscopic nephrectomy in fatal children with Wilms tumor. Rossiyskiy vestnik detskoy khirurgii, anesteziologii i reanimatologii = Journal of Pediatric Surgery, Anesthesia and Intensive Care 2018;8(3):53-9. (In Russ.).Piche N., Barrieras D. Minimally invasive nephron-sparing surgery for unilateral Wilms tumor. J Pediatr Surg 2012;47(7):e1-e4. doi: 10.1016/j.jpedsurg.2012.02.018.Piche N., Barrieras D. Minimally invasive nephron-sparing surgery for unilateral Wilms tumor. J Pediatr Surg 2012;47(7):e1-e4. doi: 10.1016/j.jpedsurg.2012.02.018.Lopes R.I., Ming J., Koyle M.A., Grant R., Fonseca A., Lorenzo A.J. “Zero-ischemia” laparoscopic-assisted partial nephrectomy for the management of selected children with Wilms’ tumors following neoadjuvant chemotherapy. Urology 2017;100:103-10. doi: 10.1016/j.urology.2016.08.051.Lopes R.I., Ming J., Koyle M.A., Grant R., Fonseca A., Lorenzo A.J. “Zero-ischemia” laparoscopic-assisted partial nephrectomy for the management of selected children with Wilms’ tumors following neoadjuvant chemotherapy. Urology 2017;100:103-10. doi: 10.1016/j.urology.2016.08.051.Cost N.G. Editorial comment on: “Zero-ischemia” laparoscopic-assisted partial nephrectomy for the management of selected children with Wilms’ tumors following neoadjuvant chemotherapy. Urology 2017;100:109. doi: 10.1016/j.urology.2016.08.052.Cost N.G. Editorial comment on: “Zero-ischemia” laparoscopic-assisted partial nephrectomy for the management of selected children with Wilms’ tumors following neoadjuvant chemotherapy. Urology 2017;100:109. doi: 10.1016/j.urology.2016.08.052.van den Heuvel-Eibrink M.M., Hol J.A., Pritchard-Jones K., van Tinteren H., Furtwangler R., Verschuur A.C., Vujanic G.M., Leuschner I., Brok J., Rube C., Smets A.M., Janssens G.O., Godzinski J., Ramfrez-Villar G.L., de Camargo B., Segers H., Collini P., Gessler M., Bergeron C., Spreafico F., Graf N. Rationale for the treatment of Wilms tumour in the UMBRELLA SIOP-RTSG 2016 protocol. Nat Rev Urol 2017;14:743-52. doi: 10.1038/nrurol.2017.163.van den Heuvel-Eibrink M.M., Hol J.A., Pritchard-Jones K., van Tinteren H., Furtwangler R., Verschuur A.C., Vujanic G.M., Leuschner I., Brok J., Rube C., Smets A.M., Janssens G.O., Godzinski J., Ramfrez-Villar G.L., de Camargo B., Segers H., Collini P., Gessler M., Bergeron C., Spreafico F., Graf N. Rationale for the treatment of Wilms tumour in the UMBRELLA SIOP-RTSG 2016 protocol. Nat Rev Urol 2017;14:743-52. doi: 10.1038/nrurol.2017.163.

The authors declare that there are no conflicts of interest present.