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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nodgo</journal-id><journal-title-group><journal-title xml:lang="ru">Российский журнал детской гематологии и онкологии (РЖДГиО)</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Pediatric Hematology and Oncology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2311-1267</issn><issn pub-type="epub">2413-5496</issn><publisher><publisher-name>LTD “Graphica”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17650/2311-1267-2015-1-75-80</article-id><article-id custom-type="elpub" pub-id-type="custom">nodgo-82</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Оригинальные исследования</subject></subj-group></article-categories><title-group><article-title>Изолированная нейтропения у детей: от педиатра к гематологу (обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>Isolated neutropenia in children: from the pediatrician to a hematologist (literature review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юдина</surname><given-names>Наталья Борисовна</given-names></name><name name-style="western" xml:lang="en"><surname>Yudina</surname><given-names>N. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Россия, 394087, Воронеж, ул. Ломоносова, 114</p></bio><bio xml:lang="en"><p>114 Lomonosov St., Voronezh, 394087, Russia</p></bio><email xlink:type="simple">n.yudina@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Брежнева</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Brezhneva</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Россия, 394087, Воронеж, ул. Ломоносова, 114</p></bio><bio xml:lang="en"><p>114 Lomonosov St., Voronezh, 394087, Russia</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>БУЗ Воронежской области «Воронежская областная детская клиническая больница № 1»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Voronezh Regional Children's Clinical Hospital № 1</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>23</day><month>05</month><year>2015</year></pub-date><volume>2</volume><issue>1</issue><fpage>75</fpage><lpage>80</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Юдина Н.Б., Брежнева Н.В., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Юдина Н.Б., Брежнева Н.В.</copyright-holder><copyright-holder xml:lang="en">Yudina N.B., Brezhneva N.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nodgo.org/jour/article/view/82">https://journal.nodgo.org/jour/article/view/82</self-uri><abstract><p>В практике детского гематолога пациенты с изолированной нейтропенией занимают определенное место, на их долю приходится около 15–20 % случаев всех обращений на консультацию к гематологу или педиатру. «Реактивный лимфоцитоз» – наиболее распространенная трактовка этого состояния специалистами «негематологического» профиля, которая приводит к определенному замешательству. В статье представлен обзор литературы с акцентом на проблему приобретенной изолированной нейтропении у детей, которая не связана с врожденной и приобретенной миелосупрессией, синдромами врожденной нейтропении, гиперспеленизмом.</p></abstract><trans-abstract xml:lang="en"><p>In the practice of pediatric hematologist, patients with isolated neutropenia occupy a certain place and account for about 15–20 % of all requests for a consultation with a hematologist or a pediatrician. “Reactive lymphocytosis” is the most common interpretation of this state by experts of “hematological” type, which leads to a certain confusion. The article presents a review of the literature with an emphasis on the problem of acquired isolated neutropenia in children, which is not associated with congenital and acquired myelosuppression, congenital neutropenia syndromes, and hyperspelenism.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>транзиторная нейтропения</kwd><kwd>хроническая аутоиммунная нейтропения</kwd><kwd>неонатальная изоиммунная нейтропения</kwd><kwd>идиосинкразия</kwd><kwd>TRALI-синдром</kwd><kwd>тяжелая хроническая нейтропения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>transient neutropenia</kwd><kwd>chronic autoimmune neutropenia</kwd><kwd>neonatal isoimmune neutropenia</kwd><kwd>idiosyncrasy</kwd><kwd>TRALI-syndrome</kwd><kwd>severe chronic neutropenia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Финогенова Н.А. Болезни лейкоцитов. Практическое руководство по детским болезням. 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