nodgoРоссийский журнал детской гематологии и онкологии (РЖДГиО)Russian Journal of Pediatric Hematology and Oncology2311-12672413-5496LTD “Graphica”10.21682/2311-1267-2023-10-2-99-106nodgo-941Research ArticleКЛИНИЧЕСКИЕ НАБЛЮДЕНИЯCLINICAL CASESКлиническое наблюдение перстневидноклеточного рака желудка у ребенка. Эндоскопическая диагностикаA clinical case of signet ring cell carcinoma of stomach in a child. Endoscopic diagnosticshttps://orcid.org/0000-0001-6262-7763ЛозоваяВ. В.LozovayaV. V.

врач-эндоскопист эндоскопического отделения НИИ клинической онкологии им. Н.Н. Трапезникова,

115522, Москва, Каширское шоссе, 23

Endoscopist of Endoscopy Department of the N.N. Trapeznikov Research Institute of Clinical Oncology,

23 Kashirskoe Shosse, Moscow, 115522

lera.lozovaya@bk.ruhttps://orcid.org/0000-0001-6179-1115ГусароваО. А.GusarovaO. A.

Ольга Андреевна Гусарова,  врач-ординатор-эндоскопист эндоскопического отделения НИИ клинической онкологии им. Н.Н. Трапезникова,

115522, Москва, Каширское шоссе, 23

Resident of Endoscopy Department of the N.N. Trapeznikov Research Institute of Clinical Oncology,

23 Kashirskoe Shosse, Moscow, 115522

o.a.gusarova@mail.ruhttps://orcid.org/0000-0003-0829-7809МалиховаО. А.MalikhovaO. A.

д.м.н., врач-эндоскопист, заведующая эндоскопическим отделением НИИ клинической онкологии им. Н.Н. Трапезникова, 115522, Москва, Каширское шоссе, 23;

профессор кафедры онкологии и паллиативной медицины, 125993, Москва, ул. Баррикадная, 2/1, стр. 1

Dr. of Sci. (Med.), Head of the Endoscopy Department of the N.N. Trapeznikov Research Institute of Clinical Oncology, 23 Kashirskoe Shosse, Moscow, 115522

Professor of the Department of Oncology and Palliative Medicine, Bld. 1, 2/1 Barrikadnaya St., Moscow, 125993

malikhova@inbox.ruhttps://orcid.org/0000-0002-1693-0523БесоваН. С.BesovaN. S.

к.м.н., ведущий научный сотрудник отделения противоопухолевой лекарственной терапии № 2 отдела лекарственного лечения,

115522, Москва, Каширское шоссе, 23

Dr. of Sci. (Med.), Leading Researcher Department of Antitumor Drug Therapy No. 2 Department of Drug Treatment,

23 Kashirskoe Shosse, Moscow, 115522

besovans@mail.ruhttps://orcid.org/0000-0002-5489-1879СулеймановаА. М.SuleymanovaA. M.

старший научный сотрудник, врач-детский онколог детского онкологического отделения № 1 (химиотерапии опухолей торакоабдоминальной локализации) НИИ детской онкологии и гематологии им. акад. РАМН Л.А. Дурнова, 

115522, Москва, Каширское шоссе, 23

Researcher, Pediatric Oncologist Pediatric Oncology Department No. 1 (Chemotherapy of Tumors of Thoracoabdominal Localization) of the Research Institute of Pediatric Oncology and Hematology named after Academician of the Russian Academy of Medical Sciences L.A. Durnov,

23 Kashirskoe Shosse, Moscow, 115522

aminasuleymanova313@gmail.comСинягинаЮ. В.SinyaginaYu. V.

к.м.н., заведующая дневным стационаром с проведением химиотерапии НИИ детской онкологии и гематологии им. акад. РАМН Л.А. Дурнова,

115522, Москва, Каширское шоссе, 23

Head of the Day Hospital with Chemotherapy of the Research Institute of Pediatric Oncology and Hematology named after Academician of the Russian Academy of Medical Sciences L.A. Durnov,

23 Kashirskoe Shosse, Moscow, 115522

yanka007@mail.ruhttps://orcid.org/0000-0001-5863-5197ТуманянА. О.TumanyanA. O.

д.м.н., старший научный сотрудник поликлинического отделения НИИ клинической онкологии им. Н.Н. Трапезникова,

115522, Москва, Каширское шоссе, 23

Dr. of Sci. (Med.), Senior Researcher Outpatient Department of the N.N. Trapeznikov Research Institute of Clinical Oncology,

23 Kashirskoe Shosse, Moscow, 115522

tumanyan.armen.o@yandex.ruФГБУ «НМИЦ онкологии им. Н.Н. Блохина» Минздрава РоссииРоссияN.N. Blokhin National Medical Research Centre of Oncology, Ministry of Health of RussiaRussian FederationФГБУ «НМИЦ онкологии им. Н.Н. Блохина» Минздрава России; ФГБОУ ДПО РМАНПО Минздрава РоссииРоссияN.N. Blokhin National Medical Research Centre of Oncology, Ministry of Health of Russia; Russian Medical Academy of Continuous Professional Education, Ministry of Health of RussiaRussian Federation20231907202310299106Copyright © Лозовая В.В., Гусарова О.А., Малихова О.А., Бесова Н.С., Сулейманова А.М., Синягина Ю.В., Туманян А.О., 20232023Лозовая В.В., Гусарова О.А., Малихова О.А., Бесова Н.С., Сулейманова А.М., Синягина Ю.В., Туманян А.О.Lozovaya V.V., Gusarova O.A., Malikhova O.A., Besova N.S., Suleymanova A.M., Sinyagina Y.V., Tumanyan A.O.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.nodgo.org/jour/article/view/941

Злокачественные новообразования (ЗНО) желудочно-кишечного тракта (ЖКТ) у детей встречаются крайне редко и составляют 1,2 % среди всех ЗНО. Согласно данным научной литературы, частота распространения рака желудка (РЖ) составляет не более чем 0,05 % среди всех случаев ЗНО ЖКТ у детей. В отечественной и зарубежной литературе описаны лишь единичные случаи РЖ у детей и подростков в возрасте от 10 до 18 лет. Клинические проявления заболевания, как и у пациентов в возрасте старше 18 лет, носят неспецифический характер – боли в эпигастрии, снижение аппетита, потеря массы тела, асцит, анемия, мелена и др. В связи с этим постановка диагноза происходит на поздних стадиях болезни и, следовательно, характеризуется неблагоприятным прогнозом. Перстневидноклеточный РЖ (ПКРЖ) является редким гистологическим подтипом аденокарциномы и встречается, как правило, у людей в возрасте от 20 до 40 лет. В данной работе представлен редкий случай развития ПКРЖ у ребенка 14 лет.

Malignant neoplasms (MNP) of the gastrointestinal tract in children are extremely rare and account for 1.2 % of all MNP. According to world literature, the incidence of gastric cancer is no more than 0.05 % of all cases of MNP of the gastrointestinal tract in children. In national and foreign literature, only isolated cases of stomach cancer in children and adolescents aged 10 to 18 years are described. Clinical manifestations of the disease, as in patients over the age of 18, are non-specific – epigastric pain, loss of appetite, weight loss, ascites, anemia, melena and others. In this regard, the diagnosis occurs at the late stages of the disease and, therefore, is characterized by an unfavorable prognosis. Gastric signet ring cell carcinoma (SRCC) is an uncommon histologic subtype of adenocarcinoma and usually occurs in people aged 20 to 40 years. We would like to report an extremely rare case of SRCC in a 14-year-old child.

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The authors declare that there are no conflicts of interest present.