A clinical case of reconstruction of the lower third of the face in an eight-year-old patient after successful complex treatment for an extrarenal rhabdoid tumor of the soft tissues of the chin
N. S. Grachev,
K. D. Starokorova,
N. M. Markov,
N. V. Babaskina,
A. V. Lopatin,
I. N. Vorozhtsov,
E. K. Gorokhova https://doi.org/10.21682/2311-1267-2024-11-2-85-89
Abstract
Malignant extrarenal rhabdoid tumor is a rare, highly aggressive neoplasm of childhood, belonging to a group of heterogeneous formations and having an extremely poor prognosis with a median survival of 2–12 months.
In this article, we present a clinical case of a female patient with a malignant extrarenal rhabdoid tumor of the soft tissues of the submandibular region, diagnosed at the age of five months. The child received comprehensive treatment and has been in remission since the age of one and a half years. Due to the prolonged absence of signs of recurrence, continued growth, and progression of the disease, a decision was made on the advisability of conducting a reconstructive plastic stage of treatment to restore the lower zone of the child’s face.
Keywords
Supporting agencies: The study was performed without external funding.
About the Authors
N. S. Grachev
Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Ministry of Health of Russia
Russian Federation
Russian Federation
Dr. of Sci. (Med.), Professor, General Director
1 Samory Mashela St., Moscow, 117997
K. D. Starokorova
Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Ministry of Health of Russia
Russian Federation
Russian Federation
Pediatric Surgeon Department of Pediatric Oncology, Head and Neck Surgery and Neurosurgery
1 Samory Mashela St., Moscow, 117997
N. M. Markov
Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Ministry of Health of Russia
Russian Federation
Russian Federation
Dr. of Sci. (Med.), Professor, Head of the Laboratory of Maxillofacial Rehabilitation, Dentistry and Orthodontics
1 Samory Mashela St., Moscow, 117997
N. V. Babaskina
Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Ministry of Health of Russia
Russian Federation
Russian Federation
Pediatric Oncologist Department of Pediatric Oncology, Head and Neck Surgery and Neurosurgery
1 Samory Mashela St., Moscow, 117997
A. V. Lopatin
Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Ministry of Health of Russia
Russian Federation
Russian Federation
Dr. of Sci. (Med.), Professor, Oral and Maxillofacial Surgeon Department of Pediatric Oncology, Head and Neck Surgery and Neurosurgery
1 Samory Mashela St., Moscow, 117997
I. N. Vorozhtsov
Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Ministry of Health of Russia
Russian Federation
Russian Federation
Cand. of Sci. (Med.),Head of the Department of Pediatric Oncology, Head and Neck Surgery and Neurosurgery
1 Samory Mashela St., Moscow, 117997
E. K. Gorokhova
Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Ministry of Health of Russia
Russian Federation
Russian Federation
Orthodontist, Researcher of the Laboratory of Maxillofacial Rehabilitation, Dentistry and Orthodontics
1 Samory Mashela St., Moscow, 117997
References
1. Nemtsova M.V., Bure I.V. Targeting of the SWI/SNF chromatin remodeling complex in cancer therapy. Uspekhi molekulyarnoy onkologii = Advances in Molecular Oncology. 2023;10(1):8–17. (In Russ.)
2. Teleshova M.V. Malignant rhabdoid tumors of soft tissues in children. Literature review. Rossiyskiy zhurnal detskoy gematologii i onkologii = Russian Journal of Pediatric Hematology and Oncology. 2017;4(4):56–66. (In Russ.)
3. Heck J.E., Lombardi C.A., Cockburn M., Meyers T.J., Wilhelm M., Ritz B. Epidemiology of rhabdoid tumors of early childhood. Pediatr Blood Cancer. 2013;60(1):77–81. doi: 10.1002/pbc.24141.
4. Mitrofanova A.M., Roshchin V.Yu., Kisliakov A.N., Abramov D.S., Rogozhin D.V., Konovalov D.M. Extrarenal rhabdoid tumor: A review of literature and a report of cases with atypical morphology. Arkhiv patologii = Pathology Archive. 2017;79(3):34–41. (In Russ.)
5. Chundriger Q., Ud Din N. Extrarenal rhabdoid tumor. PathologyOutlines.com. [Electronic resource]: https://www. pathologyoutlines.com/topic/softtissuerhabdoidtumor.html. (appeal date: 10.03.2024).
Review
For citations:
Grachev N.S., Starokorova K.D., Markov N.M., Babaskina N.V., Lopatin A.V., Vorozhtsov I.N., Gorokhova E.K. A clinical case of reconstruction of the lower third of the face in an eight-year-old patient after successful complex treatment for an extrarenal rhabdoid tumor of the soft tissues of the chin. Russian Journal of Pediatric Hematology and Oncology. 2024;11(2):85-89. (In Russ.) https://doi.org/10.21682/2311-1267-2024-11-2-85-89
Views:
260
Email this article 