Opsoclonus-myoclonus syndrome and neuroblastoma (a review of literature)
https://doi.org/10.17650/2311-1267-2014-0-1-62-69
Abstract
Opsoclonus-myoclonus syndrome (OMS) is a rare neurological disorder. Chronic neurological symptoms in patients, improperly examined and treated, and diagnostic errors during their first visit to a doctor suggest that most physicians are unaware of this syndrome and criteria for its diagnosis. The pediatrician who follows up an infant with cerebellar ataxia must know that this condition may be a manifestation of OMS. 50 % of childhood-onset OMS cases are associated with neuroblastoma (NB). However, to date difficulties have emerged in the early diagnosis of this condition and in the determination of initial examination scope and therapy policy. This paper reviews the literature on different aspects of the pathogenesis, diagnosis, clinical presentation, treatment, and prognosis of OMS. The issues of NB-associated OMS are considered separately.
About the Authors
D. Yu. Kachanov
Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitriy Rogachev, Ministry of Health of Russia
Russian Federation
Moscow
Russian Federation
Moscow
T. V. Shamanskaya
Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitriy Rogachev, Ministry of Health of Russia
Russian Federation
Moscow
Russian Federation
Moscow
O. B. Malevich
Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitriy Rogachev, Ministry of Health of Russia
Russian Federation
Moscow
Russian Federation
Moscow
S. R. Varfolomeeva
Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitriy Rogachev, Ministry of Health of Russia
Russian Federation
Moscow
Russian Federation
Moscow
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Review
For citations:
Kachanov D.Yu., Shamanskaya T.V., Malevich O.B., Varfolomeeva S.R. Opsoclonus-myoclonus syndrome and neuroblastoma (a review of literature). Russian Journal of Pediatric Hematology and Oncology. 2014;(1):62-69. (In Russ.) https://doi.org/10.17650/2311-1267-2014-0-1-62-69
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