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Российский журнал детской гематологии и онкологии (РЖДГиО)

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Преимущества и недостатки методов ядерной медицины, используемых при диагностике у пациентов с нейробластомой (обзор литературы)

https://doi.org/10.17650/2311-1267-2016-3-2-50-56

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Аннотация

На момент постановки диагноза приблизительно у 50 % пациентов с нейробластомой (НБ) определяется распространенная форма заболевания. Поэтому правильное стадирование с использованием методов лучевой диагностики и ядерной медицины имеет важнейшее значение у таких больных. Метайодбензилгуанидин (МЙБГ) является аналогом норадреналина и это идеальный туморотропный препарат для визуализации опухолевых клеток, экспрессирующих переносчики норадреналина. К основным недостаткам сцинтиграфии с МЙБГ следует отнести ограниченное пространственное разрешение, низкую чувствительность при диагностике опухолей малых размеров, существование НБ, клетки которых не накапливают МЙБГ, длительность исследования и необходимость выполнения нескольких протоколов сканирования. Позитронно-эмиссионная томография с соответствующим радиофармпрепаратом может стать хорошей альтернативой сцинтиграфии с МЙБГ и помочь при сомнительных и противоречивых результатах.

Об авторах

А. Кайлаш
ФГБУ «ФНКЦ ДГОИ им. Дмитрия Рогачева» Минздрава России
Россия

117997, Москва, ул. Саморы Машела, 1



Ю. Н. Ликарь
ФГБУ «ФНКЦ ДГОИ им. Дмитрия Рогачева» Минздрава России
Россия

117997, Москва, ул. Саморы Машела, 1



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Для цитирования:


Кайлаш А., Ликарь Ю.Н. Преимущества и недостатки методов ядерной медицины, используемых при диагностике у пациентов с нейробластомой (обзор литературы). Российский журнал детской гематологии и онкологии (РЖДГиО). 2016;3(2):50-56. https://doi.org/10.17650/2311-1267-2016-3-2-50-56

For citation:


Kailash A., Likar Y.N. Advantages and disadvantages of nuclear medicine techniques used in the diagnosis of patients with neuroblastoma (a review). Russian Journal of Pediatric Hematology and Oncology. 2016;3(2):50-56. (In Russ.) https://doi.org/10.17650/2311-1267-2016-3-2-50-56

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ISSN 2311-1267 (Print)
ISSN 2413-5496 (Online)