Treatment problem of anephric patients with Wilms tumor
R. I. Izmozherova,
S. A. Kuleva,
S. V. Ivanova,
E. D. Gumbatova,
E. M. Senchurov,
A. I. Osipov,
S. A. Sarychev,
A. G. Trofimova,
N. D. Faseeva,
E. A. Mikhailova,
K. M. Borokshinova https://doi.org/10.21682/2311-1267-2020-7-2-120-5
Abstract
Bilateral nephroblastoma is rare and is about 5 % of the total number of patients. The modern strategy of treatment children with bilateral Wilms tumor requires a comprehensive approach. An important task is to preserve as much of the renal parenchyma as possible, which will be sufficient for normal kidney function and development of the child. However, in subtotal kidney damage organ-preserving treatment is not always possible. In this case, the only curative option is bilateral nephrectomy followed by continuous renal replacement therapy. To date, the literature describes isolated cases of adjuvant chemotherapy in children on peritoneal dialysis. The article presents a clinical case of specific therapy with topotecan for a child after bilateral nephrectomy, a carrier of peritoneal dialysis catheter on the background of progression of the underlying disease.
About the Authors
R. I. Izmozherova
N.N. Petrov National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
R.I. Izmoherova, Clinical Resident of Pediatric Oncology Department
68 Leningradskaya St., Pesochny, Saint Petersburg, 197758, Russia
S. A. Kuleva
N.N. Petrov National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Dr. of Sci. (Med.), Head of Pediatric Oncology Department, Leading Researcher of the Research Department of Innovative Therapeutic Oncology and Rehabilitation Methods, Professor of the Training and Methodology Department
68 Leningradskaya St., Pesochny, Saint Petersburg, 197758, Russia
S. V. Ivanova
N.N. Petrov National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Cand. of Sci. (Med.), Pediatric Oncologist of Pediatric Oncology Department, Researcher of the Research Department of Innovative Therapeutic Oncology and Rehabilitation Methods
68 Leningradskaya St., Pesochny, Saint Petersburg, 197758, Russia
E. D. Gumbatova
N.N. Petrov National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Pediatric Oncologist of Pediatric Oncology Department
68 Leningradskaya St., Pesochny, Saint Petersburg, 197758, Russia
E. M. Senchurov
N.N. Petrov National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Pediatric Oncologist of Pediatric Oncology Department
68 Leningradskaya St., Pesochny, Saint Petersburg, 197758, Russia
A. I. Osipov
Saint-Petersburg State Pediatric Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
Cand. of Sci. (Med.), Associate Professor, Pediatric Urologist-Andrologist, Head of 1st Surgical Department
2 Litovskaya St., S.-Petersburg, 194100, Russia
S. A. Sarychev
Saint-Petersburg State Pediatric Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
Pediatric Urologist-Andrologist 1st Surgical Department
2 Litovskaya St., S.-Petersburg, 194100, Russia
A. G. Trofimova
Saint-Petersburg State Pediatric Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
Nephrologist Dialysis Department
2 Litovskaya St., S.-Petersburg, 194100, Russia
N. D. Faseeva
N.N. Petrov National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Cand. of Sci. (Med.), Pediatric Oncologist of Pediatric Oncology Department
68 Leningradskaya St., Pesochny, Saint Petersburg, 197758, Russia
E. A. Mikhailova
N.N. Petrov National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Clinical Resident of the Pediatric Oncology Department
68 Leningradskaya St., Pesochny, Saint Petersburg, 197758, Russia
K. M. Borokshinova
N.N. Petrov National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Clinical Resident of Pediatric Oncology Department
68 Leningradskaya St., Pesochny, Saint Petersburg, 197758, Russia
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For citations:
Izmozherova R.I., Kuleva S.A., Ivanova S.V., Gumbatova E.D., Senchurov E.M., Osipov A.I., Sarychev S.A., Trofimova A.G., Faseeva N.D., Mikhailova E.A., Borokshinova K.M. Treatment problem of anephric patients with Wilms tumor. Russian Journal of Pediatric Hematology and Oncology. 2020;7(2):120-125. (In Russ.) https://doi.org/10.21682/2311-1267-2020-7-2-120-5
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