A case of false-positive diagnosis of skin melanoma in a child
https://doi.org/10.21682/2311-1267-2021-8-2-103-107
Abstract
Diagnosis of skin melanoma (SM) in children is a complex clinical and morphoimmunological problem. The rare occurrence, difficult interpretation of histological and immunohistochemical picture explain the error rate in the diagnosis of SM reaching 28.8 %. This article presents a clinical case of false-positive diagnosis of SM. As a result of a detailed assessment of the anamnesis, examination, revision of histological preparations and conducting an immunohistochemical study in the reference center, the diagnosis of SM was excluded.
Supporting agencies: The team of authors would like to thank the head of the histological laboratory of the European Medical Center D.V. Bulanov for his help in the immunohistochemical study using the ultraView Universal Alkaline Phosphatase Red Detection Kit.
About the Authors
T. S. Belysheva
N.N. Blokhin National Medical Research Centre of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Dr. of Sci. (Med.), Leading Researcher Scientific Advisory Division Research Institute of Pediatric Oncology and Hematology of N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia.
23 Kashirskoe Shosse, Moscow, 115478.
Ya. V. Vishnevskaya
N.N. Blokhin National Medical Research Centre of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Cand. of Sci. (Med.), Pathologist Pathology Department Research Institute of Clinical Oncology of N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia.
23 Kashirskoe Shosse, Moscow, 115478.
A. S. Volkova
N.N. Blokhin National Medical Research Centre of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Resident of the Research Institute of Pediatric Oncology and Hematology at N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia.
23 Kashirskoe Shosse, Moscow, 115478.
T. T. Valiev
N.N. Blokhin National Medical Research Centre of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Dr. of Sci. (Med.), Head of the Children's Department of Hemoblastosis Chemotherapy of the Department of Hematology and Bone Marrow Transplantation of Research Institute of Pediatric Oncology and Hematology at the N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia.
23 Kashirskoe Shosse, Moscow, 115478.
S. N. Mikhailova
N.N. Blokhin National Medical Research Centre of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Cand. of Sci. (Med.), Head of Scientific Advisory Division Research Institute of Pediatric Oncology and Hematology of N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia.
23 Kashirskoe Shosse, Moscow, 115478.
V. G. Polyakov
N.N. Blokhin National Medical Research Centre of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Academician of RAS, Dr. of Sci. (Med.), Professor, Head of Surgery Department No. 1, Advisor to the Director of the Research Institute of Pediatric Oncology and Hematology of N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia.
23 Kashirskoe Shosse, Moscow, 115478.
SPIN-code: 8606-3120
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For citations:
Belysheva T.S., Vishnevskaya Ya.V., Volkova A.S., Valiev T.T., Mikhailova S.N., Polyakov V.G. A case of false-positive diagnosis of skin melanoma in a child. Russian Journal of Pediatric Hematology and Oncology. 2021;8(2):103-107. (In Russ.) https://doi.org/10.21682/2311-1267-2021-8-2-103-107
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