The problem of thrombophilia in clinical practice
https://doi.org/10.17650/2311-1267-2015-1-36-48
Abstract
In the lecture new perspectives are given on thrombophilia, thrombogenic risk factors and the state of thrombotic readiness preceding and accompanying critical vascular ischemia. The role of these concepts is defined by explaining the occurrence of arterial and venous thrombosis. Modern laboratory methods for the assessment of thrombogenic risk factors and thrombotic state of readiness, which help to determine the need to start thromboprophylaxis, are canceled.
About the Author
A. P. Momot
Altai Branch Hematological Research Center, Ministry of Health of Russia;
Altai State Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
1 Lyapidevskogo St., Barnaul, Altai Region, 656024, Russia;
40 Lenina Prosp., Barnaul, Altai Region, 656038, Russia
References
1. Heit J. A. Thrombophilia: Clinical and Laboratory Assessment and Manajement. In: Kitchens C. S., Kessler C. M., Konkle B. A., eds. Consultative Hemostasis and Thrombosis. 3rd ed. Philadelphia: Saunders Elsevier, 2013. Pp. 205–39.
2. Kearon C., Akl E. A., Comerota A. J. et al. Antithrombotic therapy for VTE disease: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College 3. of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 2012;141(2):e419S–94S.
3. Lopes L. C., Eikelboom J., Spencer F. A. et al. Shorter or longer anticoagulation to prevent recurrent venous thromboembolism: systematic review and meta-analysis. BMJ Open 2014;4(7):e005674.
4. McManus R.J., Fitzmaurice D. A., Murray E., Taylor C. Thromboembolism. Clin Evid 2011;2011:pii:0208.
5. Баркаган З. С., Момот А. П. Диагностика и контролируемая терапия нарушений гемостаза. М.: Ньюдиамед; 2008. [Barkagan Z. S., Momot A. P. Diagnostics and controlled therapy of violations of a hemostasis. Moscow: N, yudiamed, 2008. (In Russ.)].
6. Момот А. П., Цывкина Л. П., Тараненко И. А. и др. Современные методы распознавания состояния тромботической готовности. Барнаул: Изд-во Алтайского государственного университета, 2011. [Momot A. P., Tsyvkina L. P., Taranenko I. A. et al. Modern methods of recognition of a condition of trombotichesky readiness. Barnaul: Izd-vo Altai State University, 2011. (In Russ.)].
7. Момот А. П., Строзенко Л. А., Цывкина Л. П. и др. Первичная тромбопрофилактика у детей Алтайского края на основе выявления и модификации постоянных и временных факторов тромбогенного риска. Методические рекомендации для врачей педиатров, клинических ординаторов и интернов. Барнаул: Изд-во АГМУ, 2013. [Momot A. P., Strozenko L. A., Tsyvkina L. P. et al. Primary tromboprofilaktika at children of Altai Krai on the basis of identification and modification of constant and temporary factors of trombogenny risk. Methodical recommendations for pediatricians, clinical interns and interns. Barnaul: Izd-vo AGMU, 2013. (In Russ.)].
8. Наместников Ю. А. Тест генерации тромбина – интегральный показатель состояния системы свертывания крови. Гематология и трансфузиология 2010;2:32–9. [Namestnikov Yu. A. The test of generation of thrombin – an integrated indicator of a condition of system of a fibrillation. Gematologiya i transfuziologiya = Hematology and Blood Transfusion 2010;2:32–9. (In Russ.)].
9. Сошитова Н. П., Пантелеев М. А., Атауллаханов Ф. И. Использование глобальных методов оценки состояния гемостаза при сепсисе. Проблемы клинической медицины 2012;1:27–35. [ Soshitova N. P., Panteleev M. A., Ataullakhanov F. I. Use of global methods of an assessment of a condition of a hemostasis at sepsis. Problemy klinicheskoy meditsiny = Problems of Clinical Medicine 2012;1:27–35. (In Russ.)].
Review
For citations:
Momot A.P. The problem of thrombophilia in clinical practice. Russian Journal of Pediatric Hematology and Oncology. 2015;2(1):36-48. (In Russ.) https://doi.org/10.17650/2311-1267-2015-1-36-48
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