A clinical case of signet ring cell carcinoma of stomach in a child. Endoscopic diagnostics
V. V. Lozovaya,
O. A. Gusarova,
O. A. Malikhova,
N. S. Besova,
A. M. Suleymanova,
Yu. V. Sinyagina,
A. O. Tumanyan https://doi.org/10.21682/2311-1267-2023-10-2-99-106
Abstract
Malignant neoplasms (MNP) of the gastrointestinal tract in children are extremely rare and account for 1.2 % of all MNP. According to world literature, the incidence of gastric cancer is no more than 0.05 % of all cases of MNP of the gastrointestinal tract in children. In national and foreign literature, only isolated cases of stomach cancer in children and adolescents aged 10 to 18 years are described. Clinical manifestations of the disease, as in patients over the age of 18, are non-specific – epigastric pain, loss of appetite, weight loss, ascites, anemia, melena and others. In this regard, the diagnosis occurs at the late stages of the disease and, therefore, is characterized by an unfavorable prognosis. Gastric signet ring cell carcinoma (SRCC) is an uncommon histologic subtype of adenocarcinoma and usually occurs in people aged 20 to 40 years. We would like to report an extremely rare case of SRCC in a 14-year-old child.
About the Authors
V. V. Lozovaya
N.N. Blokhin National Medical Research Centre of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Endoscopist of Endoscopy Department of the N.N. Trapeznikov Research Institute of Clinical Oncology,
23 Kashirskoe Shosse, Moscow, 115522
O. A. Gusarova
N.N. Blokhin National Medical Research Centre of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Resident of Endoscopy Department of the N.N. Trapeznikov Research Institute of Clinical Oncology,
23 Kashirskoe Shosse, Moscow, 115522
O. A. Malikhova
N.N. Blokhin National Medical Research Centre of Oncology, Ministry of Health of Russia;
Russian Medical Academy of Continuous Professional Education, Ministry of Health of Russia
Russian Federation
Russian Federation
Dr. of Sci. (Med.), Head of the Endoscopy Department of the N.N. Trapeznikov Research Institute of Clinical Oncology, 23 Kashirskoe Shosse, Moscow, 115522
Professor of the Department of Oncology and Palliative Medicine, Bld. 1, 2/1 Barrikadnaya St., Moscow, 125993
N. S. Besova
N.N. Blokhin National Medical Research Centre of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Dr. of Sci. (Med.), Leading Researcher Department of Antitumor Drug Therapy No. 2 Department of Drug Treatment,
23 Kashirskoe Shosse, Moscow, 115522
A. M. Suleymanova
N.N. Blokhin National Medical Research Centre of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Researcher, Pediatric Oncologist Pediatric Oncology Department No. 1 (Chemotherapy of Tumors of Thoracoabdominal Localization) of the Research Institute of Pediatric Oncology and Hematology named after Academician of the Russian Academy of Medical Sciences L.A. Durnov,
23 Kashirskoe Shosse, Moscow, 115522
Yu. V. Sinyagina
N.N. Blokhin National Medical Research Centre of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Head of the Day Hospital with Chemotherapy of the Research Institute of Pediatric Oncology and Hematology named after Academician of the Russian Academy of Medical Sciences L.A. Durnov,
23 Kashirskoe Shosse, Moscow, 115522
A. O. Tumanyan
N.N. Blokhin National Medical Research Centre of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Dr. of Sci. (Med.), Senior Researcher Outpatient Department of the N.N. Trapeznikov Research Institute of Clinical Oncology,
23 Kashirskoe Shosse, Moscow, 115522
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For citations:
Lozovaya V.V., Gusarova O.A., Malikhova O.A., Besova N.S., Suleymanova A.M., Sinyagina Yu.V., Tumanyan A.O. A clinical case of signet ring cell carcinoma of stomach in a child. Endoscopic diagnostics. Russian Journal of Pediatric Hematology and Oncology. 2023;10(2):99-106. (In Russ.) https://doi.org/10.21682/2311-1267-2023-10-2-99-106
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