Differential diagnosis of teleangiectatic osteosarcoma and aneurysmal bone cyst (literature review)
Kh. A. Aleskerova,
O. M. Romantsova,
V. V. Khairullova,
M. M. Efimova,
E. V. Tyurina,
Yu. V. Sinyagina,
D. B. Khestanov,
O. A. Ignatenko,
O. V. Romanova,
D. V. Rogozhin,
T. T. Valiev,
K. I. Kirgizov https://doi.org/10.21682/2311-1267-2024-11-2-67-73
Abstract
The diagnosis of malignant neoplasms of bones often causes difficulties for doctors of all specialties. Despite the fact that many radiological features of malignant neoplasms have been identified (invasive growth, periosteal reaction, destruction of the cortical layer and the presence of a soft tissue component), instrumental diagnostics is a difficult task in making a correct diagnosis. Morphological investigation is a mandatory method for diagnosis, however, at the same time, some nosological units have a similar morphological picture. The differential diagnosis of teleangiectatic osteosarcoma and aneurysmal bone cyst is a particularly difficult task, because these two neoplasms have not only a similar histological, but also a radiological picture. The mistaken diagnoses delay the correct diagnosis and, accordingly, the start of treatment, that affects the patient’s prognosis.
Keywords
teleangiectatic osteosarcoma,
aneurysmal bone cyst,
differential diagnosis,
morphology,
instrumental diagnosis
Supporting agencies: The study was performed without external funding.
About the Authors
Kh. A. Aleskerova
N.N. Blokhin National Medical Research Centre of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Pediatric Oncologist of the Day Hospital with Chemotherapy of the Research Institute of Pediatric Oncology and Hematology named after Academician of the Russian Academy of Medical Sciences L.A. Durnov
23 Kashirskoe Shosse, Moscow, 115522
O. M. Romantsova
N.N. Blokhin National Medical Research Centre of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Pediatric Oncologist, Head of the Department No. 2 (Chemotherapy of Tumors of the Musculoskeletal System) of the Research Institute of Pediatric Oncology and Hematology named after Academician of the Russian Academy of Medical Sciences L.A. Durnov
23 Kashirskoe Shosse, Moscow, 115522
V. V. Khairullova
N.N. Blokhin National Medical Research Centre of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Pediatric Oncologist Pediatric Oncology Department No. 2 (Chemotherapy of Tumors of the Musculoskeletal System) of the Research Institute of Pediatric Oncology and Hematology named after Academician of the Russian Academy of Medical Sciences L.A. Durnov
23 Kashirskoe Shosse, Moscow, 115522
M. M. Efimova
N.N. Blokhin National Medical Research Centre of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Pediatric Oncologist Pediatric Oncology Department No. 2 (Chemotherapy of Tumors of the Musculoskeletal System) of the Research Institute of Pediatric Oncology and Hematology named after Academician of the Russian Academy of Medical Sciences L.A. Durnov
23 Kashirskoe Shosse, Moscow, 115522
E. V. Tyurina
N.N. Blokhin National Medical Research Centre of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Pediatric Oncologist Pediatric Oncology Department No. 2 (Chemotherapy of Tumors of the Musculoskeletal System) of the Research Institute of Pediatric Oncology and Hematology named after Academician of the Russian Academy of Medical Sciences L.A. Durnov
23 Kashirskoe Shosse, Moscow, 115522
Yu. V. Sinyagina
N.N. Blokhin National Medical Research Centre of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Head of the Day Hospital with Chemotherapy of the Research Institute of Pediatric Oncology and Hematology named after Academician of the Russian Academy of Medical Sciences L.A. Durnov
23 Kashirskoe Shosse, Moscow, 115522
D. B. Khestanov
N.N. Blokhin National Medical Research Centre of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Cand. of Sci. (Med.), Senior Researcher of the Pediatric Oncology Department No. 2 (Chemotherapy of Tumors of the Musculoskeletal System) of the Research Institute of Pediatric Oncology and Hematology named after Academician of the Russian Academy of Medical Sciences L.A. Durnov
23 Kashirskoe Shosse, Moscow, 115522
O. A. Ignatenko
N.N. Blokhin National Medical Research Centre of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Cand. of Sci. (Med.), Radiologist of the Pediatric Radiology Department of Consultative and Diagnostic Center
23 Kashirskoe Shosse, Moscow, 115522
O. V. Romanova
N.N. Blokhin National Medical Research Centre of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Рathologist Pathology Department of the Department of Morphological and Molecular Genetic Diagnosis of Tumors
23 Kashirskoe Shosse, Moscow, 115522
D. V. Rogozhin
N.N. Blokhin National Medical Research Centre of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Dr. of Sci. (Med.), Head of the Pathology Department of the Department of Morphological and Molecular Genetic Diagnosis of Tumors
23 Kashirskoe Shosse, Moscow, 115522
T. T. Valiev
N.N. Blokhin National Medical Research Centre of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Dr. of Sci. (Med.), Head of the Department of Pediatric Oncology and Hematology (Chemotherapy of Hemoblastosis) No. 1 of the Research Institute of Pediatric Oncology and Hematology named after Academician of the Russian Academy of Medical Sciences L.A. Durnov
23 Kashirskoe Shosse, Moscow, 115522
K. I. Kirgizov
N.N. Blokhin National Medical Research Centre of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Cand. of Sci. (Med.), Deputy Director for Scientific Work of Research Institute of Pediatric Oncology and Hematology named after Academician of the Russian Academy of Medical Sciences L.A. Durnov
23 Kashirskoe Shosse, Moscow, 115522
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For citations:
Aleskerova Kh.A., Romantsova O.M., Khairullova V.V., Efimova M.M., Tyurina E.V., Sinyagina Yu.V., Khestanov D.B., Ignatenko O.A., Romanova O.V., Rogozhin D.V., Valiev T.T., Kirgizov K.I. Differential diagnosis of teleangiectatic osteosarcoma and aneurysmal bone cyst (literature review). Russian Journal of Pediatric Hematology and Oncology. 2024;11(2):67-73. (In Russ.) https://doi.org/10.21682/2311-1267-2024-11-2-67-73
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