Depletion of alpha/beta-T-cells is a robust platform for haploidentical hematopoietic stem cell transplantation results improvement
https://doi.org/10.17650/2311-1267-2015-2-3-34-38
Abstract
An opinion on alpha/beta-T-cells depletion as effective platform for haploidentical hematopoietic stem cells transplantation (HSCT) is presented in this article. Historical aspects of the method development and improvement, advantages of this type of depletion in the modern era are presented. Effectiveness of alpha/beta-T-cell depletion for significant reduction of the risk of graft-versus-host disease and infection complications is showed. Article presented in the format of personal opinion of the head of department of the Dmitry Rogachev Federal Research Center of Pediatric Hematology, Oncology and Immunology.
About the Author
M. A. Maschan
Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitriy Rogachev, Ministry of Health of Russia; 1 Samory Mashela St., Moscow, 117198, Russia
Russian Federation
Russian Federation
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Review
For citations:
Maschan M.A. Depletion of alpha/beta-T-cells is a robust platform for haploidentical hematopoietic stem cell transplantation results improvement. Russian Journal of Pediatric Hematology and Oncology. 2015;2(3):34-38. (In Russ.) https://doi.org/10.17650/2311-1267-2015-2-3-34-38
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