Preview

Russian Journal of Pediatric Hematology and Oncology

Advanced search

Bilateral nephroblastoma in children. Description of the clinical case

https://doi.org/10.17650/2311-1267-2018-5-2-50-55

Abstract

Improving the methods of diagnostic and treating malignant neoplasms in children remain a major challenge of modern pediatrics. Despite of the achievements made in the treatment of the monolateral nephroblastoma, the ambilateral kidney dysfunction by the Wilms tumor induses a number of difficulties among the pediatric oncologist at the diagnostic phase, particularly in the setting of the strategy and tactics used in the antitumor therapy. This article represents clinical case of decreasing Bilateral nephroblastoma in children of 5 years.

About the Author

L. L. Kazakova
Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Ministry of Health of Russia
Russian Federation


References

1. Erginel B., Vural S., Akin M. et al. Wilms’ tumor: a 24-year retrospective study from a single center. Pediatr Hematol Oncol 2014;31(5):409– 14. doi: 10.3109/08880018.2014.930767.

2. Hoffer F.A. Magnetic resonance imaging of abdominal masses in the pediatric patient. Semin Ultrasound CT MR 2005;26(4):212–23. PMID: 16152736.

3. Алиев М.Д., Поляков В.Г., Менткевич Г.Л., Маякова С.А. Детская онкология. Национальное руководство. М.: Издательская группа РОНЦ, Практическая медицина, 2012. 684 с. [Aliev M.D., Polyakov V.G., Mentkevich G.L., Mayakova S.A. Pediatric oncology. National guidelines. M.: Publishing group RONTS, Practicheskaya meditsina, 2012. 684 p. (In Russ.)].

4. Peres E.M., Savasan S., Cushing В. et al. Chromosome analyses of 16 cases of Wilms tumor: different pattern in unfavorable histology. Cancer Genet Cytogenet 2004;148(1):66–70. PMID: 14697643.

5. Perotti D., Mondini P., Terenziani M. et al. WT1 gene analysis in sporadic early-onset and bilateral wilms tumor patients without associated abnormalities. J Pediatr Hematol Oncol 2005;27(4):197–201. PMID: 15838390.

6. Faria P., Beckwith J.B., Mishra K. et al. Focal versus diffuse anaplasia in Wilms tumor-new definitions with prognostic significance: a report from the National Wilms Tumor Study Group. Am J Surg Pathol 1996;20(8):909–20. PMID: 8712292.

7. Bardeesy N., Falkoff D., Petruzzi M.J. et al. Anaplastic Wilms’ tumour, a subtype displaying poor prognosis, harbours p53 gene mutations. Nat Genet 1994;7(1):91–7. doi: 10.1038/ ng0594-91.

8. Breslow N., Sharples K., Beckwith J.B. et al. Prognostic factors in nonmetastatic, favorable histology Wilms’ tumor. Results of the Third National Wilms’ Tumor Study. Cancer 1991;68(11):2345–53. PMID: 1657352.

9. Ehrlich P., Chi Y.Y., Chintagumpala M.M. et al. Results of the First Prospective Multi-institutional Treatment Study in Children With Bilateral Wilms Tumor (AREN0534): A Report From the Children’s Oncology Group. Ann Surg 2017;266(3):470–8. doi: 10.1097/ SLA.0000000000002356.


Review

For citations:


Kazakova L.L. Bilateral nephroblastoma in children. Description of the clinical case. Russian Journal of Pediatric Hematology and Oncology. 2018;5(2):50-55. (In Russ.) https://doi.org/10.17650/2311-1267-2018-5-2-50-55

Views: 1044


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2311-1267 (Print)
ISSN 2413-5496 (Online)
X