Adverse outcome of mucormycosis in patients with non-Hodgkin’s lymphoma (clinical observation)
E. A. Mikhailova,
S. A. Kuleva,
S. V. Ivanova,
E. D. Gumbatova,
A. S. Artemyeva,
A. V. Khokhlova,
I. A. Burovik,
A. B. Kosichkina https://doi.org/10.21682/2311-1267-2019-6-3-72-76
Abstract
Over the past two decades, mucormycosis has firmly taken 3rd place among invasive mycoses after candidiasis and aspergillosis in patients with oncohematological diseases. The article presents a clinical case of disseminated mucormycosis that developed in a child with nonHodgkin’s lymphoma on the background of deep immunosuppression.
About the Authors
E. A. Mikhailova
N.N. Petrov National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Clinical Resident of the Department of Chemotherapy and Combined Treatment of Malignant Tumors in Children,
SPIN-code: 2940-2186
68 Leningradskaya St., Pesochny, Saint Petersburg, 197758
S. A. Kuleva
N.N. Petrov National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Dr. of Sci. (Med.), Head of the Department of Chemotherapy and Combined Treatment of Malignant Tumors in Children, Leading Researcher of the Research Department of Innovative Therapeutic Oncology and Rehabilitation Methods, Professor of the Training and Methodology Department, SPIN-code: 3441-4820
68 Leningradskaya St., Pesochny, Saint Petersburg, 197758
S. V. Ivanova
N.N. Petrov National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Cand. of Sci. (Med.), Pediatric Oncologist Department of Chemotherapy and Combined Treatment of Malignant Tumors
in Children, SPIN-code: 7834-0152
68 Leningradskaya St., Pesochny, Saint Petersburg, 197758
E. D. Gumbatova
N.N. Petrov National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Cand. of Sci. (Med.), Pediatric Oncologist of Department of Chemotherapy and Combined Treatment of Malignant Tumors in Children, SPIN-code: 6082-3330
68 Leningradskaya St., Pesochny, Saint Petersburg, 197758
A. S. Artemyeva
N.N. Petrov National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Cand. Sci. (Med.), Head of the Department of Pathomorphology, SPIN-code: 5760-5463
68 Leningradskaya St., Pesochny, Saint Petersburg, 197758
A. V. Khokhlova
N.N. Petrov National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Pathologist of Department of Pathology, SPIN-code: 9235-0099
68 Leningradskaya St., Pesochny, Saint Petersburg, 197758
I. A. Burovik
N.N. Petrov National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Cand. of Sci. (Med.), Radiologist of Radiology Department; SPIN-code: 1923-6457
68 Leningradskaya St., Pesochny, Saint Petersburg, 197758
A. B. Kosichkina
N.N. Petrov National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Radiologist of Radiology Department; SPIN-code: 2802-6529
68 Leningradskaya St., Pesochny, Saint Petersburg, 197758
References
1. Bagirova N.S. Invasive zygomycosis: epidemiology and clinical features (literature review). Onkogematologiya = Oncohematology 2016;9(1):84–9. (In Russ.)
2. Klimko N.N., Khostelidi S.N., Shadrivova O.V., Bogomolova T.S., Avdeenko Y.L., Volkova A.G., Popova M.O., Mihailova I.A., Kolbin A.S., Boychenko E.G., Medvedeva N.V., Podoltseva E.I., Klimovich A.V., Belogurova M.B., Zuzgin I.S., Uspenskaya O.S., Semelev V.N., Ponomoreva N.I., Abdilova G.K., Zuborovskaya L.S., Afanasiev B.V. Invasive mukormikoz from oncohematological patients (results of a prospective study). Onkogematologiya = Oncohematology 2017;12(2):14–22. (In Russ.)
3. Hostelidi S.N., Volkova A.G., Popova M.O., Bogomolova T.S., Kolbin A.S., Boychenko E.G., Podoltseva E.I., Klimovich A.V., Belogurova M .B., Medvedeva N.V., Zyuzgin I.S., Zubarovskaya L.S., Vasilyeva N.V., Klimko N.N. Invasive mucormycosis in patients with hemoblastosis in St.-Petersburg. Antibiotiki i Khimioterapiya = Antibiotics and Chemotherapy 2013;58(7–8):23–9. (In Russ.)
4. Baddley J.W. Clinical risk factors for invasive aspergillosis. Med Mycol 2011;49(Suppl. l):7–12. doi: 10.3109/13693786.2010.505204.
5. Vasilyeva N.V., Klimko N.N., Zinserling V.A. Modern recommendations for diagnosis and treatment of invasive myсoses. Vestnik Sankt-Peterburgskoy meditsinskoy akademii poslediplomnogo obrazovaniya = Vestnik of Saint Petersburg Medical Academy of Postgraduate Education 2010;5–18. (In Russ.)
6. Solopova G.G., Rachkov V.E., Uskova N.G., Оganesyan R.S., Konovalov D.M., Novichkova G.A. Mucormycosis of gastrointestinal localization in a patient with acute myeloblastic leukemia. Voprosy gematologii/onkologii i immunopatologii v pediatrii = Pediatric Hematology/Oncology and Immunopathology 2014;13(4):69–74. (In Russ.)
7. Tissot F., Agrawal S., Pagano L., Petrikkos G., Groll A.H., Skiada A., Lass-Flörl C., Calandra T., Viscoli C., Herbrecht R. ECIL-6 guidelines for the treatment of invasive candidiasis, aspergillosis and mucormycosis in leukemia and hematopoietic stem cell transplant patients. Haematologica. 2017;102(3):433–44. doi: 10.3324/haematol.2016.152900.
Review
For citations:
Mikhailova E.A., Kuleva S.A., Ivanova S.V., Gumbatova E.D., Artemyeva A.S., Khokhlova A.V., Burovik I.A., Kosichkina A.B. Adverse outcome of mucormycosis in patients with non-Hodgkin’s lymphoma (clinical observation). Russian Journal of Pediatric Hematology and Oncology. 2019;6(3):72-76. (In Russ.) https://doi.org/10.21682/2311-1267-2019-6-3-72-76
Views:
810
Email this article 