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Первичные лимфомы центральной нервной системы у детей и подростков

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Аннотация

Первичные лимфомы центральной нервной системы (ПЛЦНС) являются очень редким и одним из самых агрессивных вариантов экстранодальных неходжкинских лимфом (НХЛ). ПЛЦНС составляют от 4 до 7 % злокачественных опухолей центральной нервной системы у взрослых, а их истинная частота у детей неизвестна. В последние несколько десятилетий встречаемость ПЛЦНС растет, что, возможно, связано с увеличением числа лиц с первичными и вторичными иммунодефицитами, хотя ПЛЦНС диагностируются и у лиц без иммунодефицитных состояний. В связи с редкой частотой встречаемости ПЛЦНС у детей и подростков клинико-морфоиммунологические особенности данного экстранодального варианта НХЛ нуждаются в обобщении и систематизации. Не менее актуальной проблемой является выбор тактики терапии ПЛЦНС в педиатрии. В настоящем обзоре представлен мировой и отечественный опыт диагностики и лечения ПЛЦНС у детей и подростков. 

Об авторах

Т. Ю. Павлова
ФГБУ «НМИЦ онкологии им. Н.Н. Блохина» Минздрава России
Россия

врач-детский онколог детского отделения химиотерапии гемобластозов отдела гематологии и трансплантации костного мозга,

115478, Москва, Каширское шоссе, 23



Т. Т. Валиев
ФГБУ «НМИЦ онкологии им. Н.Н. Блохина» Минздрава России
Россия

д.м.н., заведующий детским отделением химиотерапии гемобластозов отдела гематологии и трансплантации костного мозга,

115478, Москва, Каширское шоссе, 23



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Для цитирования:


Павлова Т.Ю., Валиев Т.Т. Первичные лимфомы центральной нервной системы у детей и подростков. Российский журнал детской гематологии и онкологии (РЖДГиО). 2021;8(1):43-49.

For citation:


Pavlova T.Yu., Valiev T.T. Primary central nervous system lymphomas in children and adolescents. Russian Journal of Pediatric Hematology and Oncology. 2021;8(1):43-49. (In Russ.)

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