The use of proton radiation therapy in a patient with melanotic neuroectodermal tumor of infants of the anterior fontanel: description of a clinical case
https://doi.org/10.21682/2311-1267-2022-9-1-60-66
Abstract
Melanotic neuroectodermal tumor (MNET) of infants is a rare benign neoplasm detected mainly in children of the first year of life. Standard therapy consists of radical surgical removal of the tumor. Currently, the treatment of patients with recurrent and unresectable forms of the disease is relevant. The number of publications using polychemotherapy and radiation therapy is extremely limited. This article describes a clinical case of the occurrence of MNET in the anterior fontanel with a recurrent course. Proton radiation therapy was chosen as an alternative treatment method.
About the Authors
N. D. FaseevaRussian Federation
Cand. of Sci. (Med.), Pediatric Oncologist Department of Pediatric Oncology
Saint-Petersburg
N. I. Martynova
Russian Federation
Radiation Therapist Clinics Radiosurgery, Stereotactic Radiotherapy and General Oncology
Saint-Petersburg
M. D. Maksimov
Russian Federation
Trainee-doctor
Saint-Petersburg
K. F. Boyko
Russian Federation
Pediatric Oncologist, Head of the Department of Pediatric Oncology
Saint-Petersburg
N. A. Vorobyev
Russian Federation
Cand. of Sci. (Med.), Radiation Therapist, Head of the Department Proton Radiotherapy; Assistant Professor Department of Oncology; Assistant Professor Department of Oncology
Saint-Petersburg
N. A. Berezina
Russian Federation
Cand. of Sci. (Med.), Radiologist Head Doctor
Saint-Petersburg
N. A. Plakhotina
Russian Federation
Cand. of Sci. (Med.), Radiologist
Saint-Petersburg
D. A. Reshchikov
Russian Federation
Neurosurgeon
Moscow
I. G. Vasiliev
Russian Federation
Neurosurgeon
Moscow
R. B. Mai
Russian Federation
Neurosurgeon
Moscow
M. A. Titova
Russian Federation
Resident
Saint-Petersburg
O. G. Zheludkova
Russian Federation
Dr. of Sci. (Med.), Professor, Expert of the Higher Attestation Commission on Pediatric Neuro-Oncology, Pediatric Oncologist
Saint-Petersburg
Moscow
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Review
For citations:
Faseeva N.D., Martynova N.I., Maksimov M.D., Boyko K.F., Vorobyev N.A., Berezina N.A., Plakhotina N.A., Reshchikov D.A., Vasiliev I.G., Mai R.B., Titova M.A., Zheludkova O.G. The use of proton radiation therapy in a patient with melanotic neuroectodermal tumor of infants of the anterior fontanel: description of a clinical case. Russian Journal of Pediatric Hematology and Oncology. 2022;9(1):60-66. (In Russ.) https://doi.org/10.21682/2311-1267-2022-9-1-60-66