CLINICAL CASE OF BIPHENOTYPIC ACUTE LEUKAEMIA A CHILD WITH WILLIAMS SYNDROME
https://doi.org/10.17650/2311-1267-2015-2-2-89-92
Abstract
In recent decades impressive results were achieved in the treatment of children»s acute leukemia. Anyway, there are some rare forms of such tumors, for which till the present time the tactic is unknown. To such diseases are referred acute biphenotypic leukemia (ABL), which is very rare at children, so it is difficult for clinicians to determine the treatment program. ABL is diagnosed, when the simultaneous expression of antigens of different hemopoietic is revealed on blast cells. The forecast for children is unknown and the adults, forecast is unfavorable. The optimal treatment approach is also unknown, but should comprise the high-dose chemotherapy, as well as the allogeneic stem cell transplantation. Nowadays this rare form of leukemia is being intensively studied by molecular, immunologic and cytogenic methods. The work presents the analysis of a clinical case of ABL at a child with Williams syndrome.
About the Author
V. V. Shestakova
Northern State Medical University, Ministry of Health of Russia; 51 Troitsky Prosp., Аrkhangelsk, 163000, Russia
Russian Federation
Russian Federation
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Review
For citations:
Shestakova V.V. CLINICAL CASE OF BIPHENOTYPIC ACUTE LEUKAEMIA A CHILD WITH WILLIAMS SYNDROME. Russian Journal of Pediatric Hematology and Oncology. 2015;2(2):89-92. (In Russ.) https://doi.org/10.17650/2311-1267-2015-2-2-89-92
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