Полипрагмазия в практике детского онколога

На сегодняшний день проблема полипрагмазии является крайне актуальной для всех медицинских направлений, однако в онкопедиатрии определяется преимущественно особенностями лечения основного заболевания, включая комбинированные режимы противоопухолевой терапии, а также необходимостью коррекции ассоциированных мультисистемных осложнений с использованием различных классов лекарственных препаратов. Ключевыми рисками полипрагмазии являются увеличение вероятности межлекарственных взаимодействий, нежелательных лекарственных реакций, развития когнитивных нарушений, продолжительности госпитализаций, а также снижение эффективности лечения и качества жизни пациентов. При этом следует отметить малочисленность исследований, посвященных проблеме оптимизации назначения лекарственной терапии. В данной статье приведены основные понятия полипрагмазии и рассмотрены существующие практические стратегии управления навыками назначения лекарственной терапии в детской онкологии.

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