Allogeneic transplantation of hematopoietic stem cells in congenital pyruvate kinase deficiency. Case report
https://doi.org/10.21682/2311-1267-2026-13-1-104-111
Abstract
Hemolytic anemia due to pyruvate kinase deficiency is a rare congenital disease caused by a defect in the glycolytic pathway. This anemia is the most common among all enzymopathies. There are various treatment methods for this disease. This article presents a clinical case of a successful allogeneic hematopoietic stem cell transplantation in a patient with pyruvate kinase deficiency.
About the Authors
B. M. Kurmanov
Morozov Children’s City Clinical Hospital of the Moscow City Healthcare Department
Russian Federation
Russian Federation
Pediatric Hematologist of Department of HSCT
1/9 4th Dobryninskiy Per., Moscow, 119049
E. A. Burtsev
Morozov Children’s City Clinical Hospital of the Moscow City Healthcare Department
Russian Federation
Russian Federation
Head of Department of HSCT
1/9 4th Dobryninskiy Per., Moscow, 119049
I. O. Vlasova
Morozov Children’s City Clinical Hospital of the Moscow City Healthcare Department
Russian Federation
Russian Federation
Hematologist of Department of HSCT
1/9 4th Dobryninskiy Per., Moscow, 119049
E. A. Zhuravel
Morozov Children’s City Clinical Hospital of the Moscow City Healthcare Department
Russian Federation
Russian Federation
Pediatric Oncologist of Department of HSCT
1/9 4th Dobryninskiy Per., Moscow, 119049
E. V. Kumirova
Morozov Children’s City Clinical Hospital of the Moscow City Healthcare Department; N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
Dr. of Sci. (Med.), Professor, Pediatric Oncologist, Deputy Chief Physician for Oncology; Head of Department of Pediatric Palliative Care
1/9 4th Dobryninskiy Per., Moscow, 119049
1 Ostrovityanova St., Moscow, 117997
S. I. Valieva
Morozov Children’s City Clinical Hospital of the Moscow City Healthcare Department; N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
Dr. of Sci. (Med.), Professor, Deputy Chief Physician for Medical Affairs, Scientific and Educational Work; Professor of the Department of Pediatrics named after Academician M.Ya. Studenikin of the Institute of Clinical Medicine
1/9 4th Dobryninskiy Per., Moscow, 119049
1 Ostrovityanova St., Moscow, 117997
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For citations:
Kurmanov B.M., Burtsev E.A., Vlasova I.O., Zhuravel E.A., Kumirova E.V., Valieva S.I. Allogeneic transplantation of hematopoietic stem cells in congenital pyruvate kinase deficiency. Case report. Russian Journal of Pediatric Hematology and Oncology. 2026;13(1):104-111. (In Russ.) https://doi.org/10.21682/2311-1267-2026-13-1-104-111
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