Clinical case of spontaneous remission of acute myeloblastic leukemia in a patient with reactivation of cytomegalovirus infection and subsequent repeated rejections of a hemopoietic graft caused by cytotoxic lymphocytes
https://doi.org/10.17650/2311-1267-2018-5-2-45-49
Abstract
Cytomegalovirus (CMV) infection is one of the most an issue of common complications among patients receiving polychemotherapy. However, the question of the influence of CMV infection remains under-explored outside the context of allogeneic transplantation of hematopoietic stem cells. The article presents a rare clinical case – achievement of complete clinical and hematological remission of refractory neuraleukemia against CMV infection in a patient with acute myeloblastic leukemia, followed by rejection of hematopoietic transplants against the background of activation of the TcRα/β-clone of lymphocytes and CMV viremia.
About the Author
A. V. Mezentseva
Russian Children’s Clinical Hospital, Ministry of Health of Russia
Russian Federation
Russian Federation
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Review
For citations:
Mezentseva A.V. Clinical case of spontaneous remission of acute myeloblastic leukemia in a patient with reactivation of cytomegalovirus infection and subsequent repeated rejections of a hemopoietic graft caused by cytotoxic lymphocytes. Russian Journal of Pediatric Hematology and Oncology. 2018;5(2):45-49. (In Russ.) https://doi.org/10.17650/2311-1267-2018-5-2-45-49
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