Limb salvage surgery as a priority direction in the combined treatment of bone sarcomas
https://doi.org/10.21682/2311-1267-2020-7-4-82-85
Abstract
Currently a priority in children oncology is a limb salvage treatment. Achieved in recent years advances in chemotherapy of malignant bone tumors, improved surgical techniques, and also introduction in orthopedics of the newest technologies allow to considerably expand the indications for endoprosthesis. A feature in cases in children of early age is the use of sliding implants type non-invasive and minimally invasive that subsequently allows gradual correction of leg length and avoid the various disorders of musculoskeletal system (shortened limbs, spinal deformity), thereby improving the quality of life of patients. In some cases, for example, when a tumor is localized in the upper limb region, the optimal solution may be the use of autologous grafts on microvascular anastomoses. In the case of tumor localization in the pelvic region, the use of implants made by means of 3D-modeling, in our opinion, is also an optimal solution.
About the Authors
A. Z. Dzampaev
N.N. Blokhin National Medical Research Centre of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Cand. of Sci. (Med.), Head of Surgical Department № 3 of the Department of General Oncology Research Institute of Pediatric Oncology and Hematology of N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia.
23 Kashirskoe Shosse, Moscow, 115478.
D. V. Nisichenko
N.N. Blokhin National Medical Research Centre of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Cand. of Sci. (Med.), Senior Researcher of Surgical Department № 3 of the Department of General Oncology Research Institute of Pediatric Oncology and Hematology of N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia.
23 Kashirskoe Shosse, Moscow, 115478.
SPIN-code: 2597-1880
D. B. Hestanov
N.N. Blokhin National Medical Research Centre of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Cand. of Sci. (Med.), Senior Researcher of Surgical Department № 3 of the Department of General Oncology Research Institute of Pediatric Oncology and Hematology of N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia.
23 Kashirskoe Shosse, Moscow, 115478.
SPIN-code: 9756-1732
References
1. Abudu A., Grimer R., Tillman R., Carter S. The use of prostheses in skeletally immature patients. Orthop Clin North Am 2006;37(1):75-84. doi: 10.1016/j.ocl.2005.08.008.
2. Brown K.L. Resection, rotationplasty, and femoropelvic arthrodesis in severe congenital femoral deficiency. A report of the surgical technique and three cases. J Bone Joint Surg Am 2001;83(1):78-85. doi: 10.2106/00004623-200101000-00011.
3. Dominkus M., Krepler P., Schwameis E., Windhager R., Kotz R. Growth prediction in extendable tumor prostheses in children. Clin Orthop Relat Res 2001;(390):212-20. doi: 10.1097/00003086-200109000-00024.
4. Eckardt J.J., Kabo J.M., Kelley C.M., Ward W.G., Asavamongkolkul A., Wirganowicz P.Z., Yang R.S., Eilber F.R. Expandable endoprosthesis reconstruction in skeletally immature patients with tumors. Clin Orthop Relat Res 2000;(373):51-61. doi: 10.1097/00003086-200004000-00008.
5. Enneking W.F., Dunham W., Gebhardt M.C., Malawar M., Pritchard D.J. A system for the functional evaluation of reconstructive procedures after surgical treatment of tumors of the musculoskeletal system. Clin Orthop Relat Res 1993;(286):241-6. PMID: 8425352.
6. Keohan M.L., Taub R.N. Chemotherapy for advanced sarcoma: therapeutic decisions and modalities. Semin Oncol 1997;24(5):572-9. PMID: 9344324.
7. Letson G.D., D'Amato G., Windham T.C., Muro-Cacho C.A. Extendable prostheses for the treatment of malignant bone tumors in growing children. Curr Opin Orthop 2003;14:413-8. doi: 10.1097/00001433-200312000-00010.
8. Lewis V.O. Limb salvage in the skeletally immature patient. Curr Oncol Rep 2005;7(4):285-92. doi: 10.1007/s11912-005-0052-7.
9. Malawer M. Surgical technique and results of limb sparing surgery for high grade bone sarcomas of the knee and shoulder. Orthopedics 1985;8(5):597-607. PMID: 3006004.
10. Neel M.D., Letson G.D. Modular endoprostheses for children with malignant bone tumors. Cancer Control 2001;8(4):344-8. doi: 10.1177/107327480100800406.
11. Simon M.A., Aschliman M.A., Thomas N., Mankin H.J. Limb-salvage treatment versus amputation for osteosarcoma of the distal end of the femur 1986. J Bone Joint Surg Am 2005;87(12):2822. doi: 10.2106/JBJS.8712.cl.
12. Tillman R.M., Grimer R.J., Carter S.R., Cool W.P., Sneath R.S. Growing endoprostheses for primary malignant bone tumors. Semin Surg Oncol 1997;13(1):41-8. doi: 10.1002/(sici)1098-2388(199701/02)13:1<41::aid-ssu7>3.0.co;2-4.
Review
For citations:
Dzampaev A.Z., Nisichenko D.V., Hestanov D.B. Limb salvage surgery as a priority direction in the combined treatment of bone sarcomas. Russian Journal of Pediatric Hematology and Oncology. 2020;7(4):82-85. (In Russ.) https://doi.org/10.21682/2311-1267-2020-7-4-82-85
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